2012—2021年大连地区体检人群心血管疾病危险因素特征分析  

Analysis of cardiovascular risk factors in healthy screening population in Dalian from 2012 to 2021

作　　者：贾雪妮 王翠翠 赵雨龙 胡滨[1] 赵辉[1] Jia Xueni;Wang Cuicui;Zhao Yulong;Hu Bin;Zhao Hui(Health Management Center,the Second Hospital of Dalian Medical University,Dalian 116023,China;Department of Gastroenterology,Xijing 986 Hospital,Fourth Military Medical University,Xi’an 710000,China)

机构地区：[1]大连医科大学附属第二医院健康管理中心,116023 [2]空军第九八六医院消化科,西安710000

出　　处：《中国心血管杂志》2024年第6期563-570,共8页Chinese Journal of Cardiovascular Medicine

基　　金：辽宁省教育厅基本科研项目(JYTMS20230602)。

摘　　要：目的调查大连地区体检人群心血管疾病危险因素患病率及其变化趋势,并进一步分析该地区心血管疾病危险因素两两共存情况。方法回顾性研究。收集2012—2021年于大连医科大学附属第二医院健康管理中心进行体检且年龄≥20岁人群的体检数据155654人次,分别评估总人次和不同性别人次心血管疾病危险因素(高血压、超重、肥胖、血糖升高、血脂异常)粗患病率,并依据2020年第七次全国人口普查数据对患病率进行直接标准化。应用Joinpoint对数线性回归模型计算总人次及不同性别人次心血管疾病危险因素标化患病率的平均年度变化百分比(AAPC),进一步分析5种心血管疾病危险因素(高血压、超重、肥胖、血糖升高、血脂异常)10年来变化趋势及两两共存发生情况。结果2012—2021年,在5种因素中,超重粗患病率及标化患病率始终最高,其标化患病率在2020年最高(61.1%),在2019年最低(36.4%);血糖升高的粗患病率及标化患病率始终处于较低水平,血糖升高标化患病率在2021年最高(24.0%),在2013年最低(18.4%)。2012—2021年,血糖升高的粗患病率呈上升趋势(AAPC=2.8%,95%CI:0.2%~5.5%,P=0.039),而其余4种危险因素均未见明显变化。2012—2021年,男性5种危险因素粗患病率及标化患病率均远高于女性。女性高血压标化患病率由2012年的18.9%上升到2021年的21.6%(AAPC=5.0%,95%CI:0.4%~9.9%,P=0.036)。超重和血糖升高粗患病率及标化患病率在不同性别间均较稳定。肥胖粗患病率在男性呈上升趋势(AAPC=1.3%,95%CI:0.1%~2.5%,P=0.036)。血脂异常的粗患病率及标化患病率在男性中未见明显变化,而在女性粗患病率中呈上升趋势(AAPC=6.6%,95%CI:2.1%~11.3%,P=0.009)。男性超重标化患病率始终最高,女性血脂异常标化患病率最高。男性高血压标化患病率变化值为负值且绝对变化值最大,女性血脂异常年龄标化患病率变化值为正值且绝对�Objective To investigate the prevalence and trends of cardiovascular risk factors in healthy screening population in Dalian from 2012 to 2021.Methods A retrospective study was conducted.Healthy screening data of 155654 individuals aged≥20 years at the Health Management Center of the Second Hospital of Dalian Medical University from 2012 to 2021 were collected,and the crude prevalence of cardiovascular risk factors(hypertension,overweight,obesity,elevated blood sugar and dyslipidemia)was evaluated in total and stratified by gender.Prevalence rates were directly standardized based on the seventh national census data in 2020.The Joinpoint log-linear regression model was used to calculate the average annual percentage change(AAPC)of the standardized prevalence of cardiovascular risk factors in the total population and different genders,and to further analyze the change trend and pairwise cooccurrence of five cardiovascular risk factors in the past 10 years.Results From 2012 to 2021,among the five risk factors,the crude and standardized prevalence of overweight were always the highest,the standardized prevalence was the highest in 2020(61.1%),and the lowest in 2019(36.4%).The crude and standardized prevalence of elevated blood glucose remained low,with the highest prevalence of elevated blood glucose in 2021(24.0%)and the lowest prevalence of elevated blood glucose in 2013(18.4%).From 2012 to 2021,the crude prevalence of hyperglycemia showed an increasing trend(AAPC=2.8%,95%CI:0.2%-5.5%,P=0.039),while no significant changes were observed in the other 4 risk factors.From 2012 to 2021,the crude and standardized prevalence rates of five risk factors in males were much higher than those in females.The standardized prevalence of hypertension in women increased from 18.93%in 2012 to 21.61%in 2021(AAPC=5.0%,95%CI:0.4%-9.9%,P=0.036).The crude and standardized prevalence rates of overweight and elevated blood glucose were stable between different genders.Crude prevalence of obesity was increasing in males(AAPC=1.3%,95%CI:0.1

关 键 词：心血管疾病 危险因素 患病率 平均年度变化百分比 

分 类 号：R54[医药卫生—心血管疾病]