三维高分辨压缩感知对比增强全身MRA技术的可行性研究  

Feasibility study of 3D high-resolution compressed sensing contrast-enhanced whole-body MRAimaging technology

作　　者：李景阳 富青 刘小明 吴佳威 金腾 于群[1,2] 雷子乔 孔祥闯[1,2] LI Jingyang;FU Qing;LIU Xiaoming;WU Jiawei;JIN Teng;YU Qun;LEI Ziqiao;KONG Xiangchuang(Department of Radiology,Union Hospital of Tongji Medical College of Huazhong University of Science and Technology,Wuhan 430022,China;Hubei Province Key Laboratory of Molecular Imaging,Wuhan 430022,China)

机构地区：[1]华中科技大学同济医学院附属协和医院放射科,武汉430022 [2]分子影像湖北省重点实验室,武汉430022

出　　处：《磁共振成像》2024年第11期123-129,共7页Chinese Journal of Magnetic Resonance Imaging

摘　　要：目的研究单次注射、半剂量对比剂三维高分辨压缩感知对比增强全身磁共振血管造影(3D high-resolution compressed sensing contrast-enhanced whole-body magnetic resonance angiography,3D-CS-CE-MRA)的可行性和临床应用价值。材料与方法前瞻性收集83例临床怀疑全身动脉疾病前来行磁共振全身血管检查的患者,随机分为A、B两组,A组44例,B组39例。A组行3D-CS-CE-MRA扫描,对比剂总量为0.15 mmol/kg,单次注射,流速为2 m L/s;B组行常规三维高分辨对比增强全身磁共振血管造影(3D high-resolution contrast-enhanced whole-body magnetic resonance angiography,3D-CE-MRA)扫描,对比剂总量为0.3 mmol/kg,分两次注射,每次用量均为0.15 mmol/kg,流速为2 m L/s。两名经验丰富的放射科医生独立分析两组25个动脉节段的图像质量,并对各段动脉进行评分;选取颈总动脉、腹主动脉、股动脉、腘动脉测量信噪比(signal-to-noise ratio,SNR)和对比噪声比(contrast-to-noise ratio,CNR),进行定量分析。采用独立样本t检验、Wilcox秩和检验进行统计分析。结果SNR_(颈总)、SNR_(股动脉)、SNR_(腘动脉)、CNR_(颈总)、CNR_(股动脉)、CNR_(腘动脉)总体测量结果差异无统计学意义(P均<0.05),SNR_(腹主)、CNR_(腹主)总体测量结果差异有统计学意义(P均<0.05),B组均值高于A组。3D-CS-CE-MRA平均得分优于3D-CE-MRA[(3.41±0.52)vs.(3.18±0.48),P<0.05];腹主动脉、肾动脉、肠系膜上动脉、腹腔干、髂总动脉、髂外动脉、胫前动脉、腓动脉血管显示评分差异无统计学意义(P均>0.05),A、B两组图像质量差异无统计学意义;颈总动脉、头臂干、椎动脉、胸主动脉、股动脉、腘动脉、胫后动脉血管显示评分差异有统计学意义(P均<0.05),A组评分高于B组。结论与常规3D-CE-MRA相比,3D-CS-CE-MRA只需一次对比剂注射且无需减影即可快速完成磁共振全身血管检查,在保证图像质量的前提下,减少了对比剂用量,缩短了检查时�Objective:To investigate the feasibility and clinical value of 3D high-resolution compressed sensing contrast-enhanced whole-body magnetic resonance angiography(3D-CS-CE-MRA)with single injection and half-dose contrast agent.Materials and Methods:A total of 83 patients who were suspected of systemic arterial disease and underwent MRI systemic vascular examination were prospectively enrolled and randomly divided into two groups,A and B,with 44 patients in group A and 39 patients in group B.Group A underwent 3D-CS-CE-MRA scanning with a total contrast agent volume of 0.15 mmol/kg injected at a flow rate of 2 mL/s,while group B underwent conventional 3D high-resolution contrast-enhanced whole-body magnetic resonance angiography(3D-CE-MRA)scanning with a total contrast agent volume of 0.3 mmol/kg administered in two doses of 0.15 mmol/kg each at a flow rate of 2 mL/s.Two experienced radiologists independently scored the qualitative image quality of 25 arterial segments,and signal-to-noise ratio(SNR)and contrast-to-noise ratio(CNR)were measured for the common carotid artery,abdominal aorta,femoral artery,and popliteal artery.The independent samples t-test and the Wilcoxon rank sum test was used for statistical analysis.Results:There was no significant difference in SNRs and CNRs for the common carotid artery,the femoral artery and the popliteal artery(all P>0.05),but there was significant difference in SNRs and CNRs for the abdominal aorta(all P<0.05),the average value of group B was higher than that of group A.The average score of 3D-CS-CE-MRA was better than 3D-CE-MRA[(3.41±0.52)vs.(3.18±0.48),P<0.05].There was no significant difference in scores of abdominal aorta,renal artery,superior mesenteric artery,celiac trunk,common iliac artery,external iliac artery,anterior tibial artery,and peroneal artery(all P>0.05);there was no difference in image quality between group A and B.There was significant difference in scores of common carotid artery,brachiocephalic trunk,vertebral artery,thoracic aorta,femoral artery,popli

关 键 词：磁共振成像 压缩感知 多回波Dixon 对比增强 全身磁共振血管造影 

分 类 号：R445.2[医药卫生—影像医学与核医学] R543.5[医药卫生—诊断学]