CKM:一种新的综合征还是代谢综合征的心肾表征  

CKM:A new syndrome or a phenotype of metabolic syndrome

作　　者：曲伸[1] Qu Shen(Obesity Diagnosis and Treatment Center,Shanghai Tenth People's Hospital,Shanghai 200072,Chind)

机构地区：[1]上海市第十人民医院肥胖症诊治中心,上海200072

出　　处：《中华内分泌代谢杂志》2024年第11期923-926,共4页Chinese Journal of Endocrinology and Metabolism

基　　金：国家自然科学基金(82170861, 81970677)。

摘　　要：心血管-肾脏-代谢(CKM)综合征描述了肥胖、糖尿病、慢性肾脏疾病和心血管疾病之间复杂的相互作用, 反映了对多系统疾病相互关系的深入理解, 为研究和治疗这些疾病提供了依据, 但在诊断标准和临床适用性上仍存在挑战。综合征的提出需从病因出发, 由繁及简, 控一因而利全局。本文解析了2型糖尿病、肥胖、心血管疾病和慢性肾病间的关联及相互作用, 并对CKM的定义和命名进行了探讨, 以期为临床诊疗提供合理有效的帮助。Cardiovascular-kidney-metabolic(CKM)syndrome encapsulates the intricate interplay among obesity,diabetes mellitus,chronic kidney disease,and cardiovascular diseases.This concept reflects a deeper understanding of their interconnection,and provides a foundation for research,though challenges remain in establishing diagnostic criteria and clinical applicability.Addressing the syndrome from its root causes could simplify management by targeting key factors that influence the broader condition.This article examines the relationships among type 2 diabetes,obesity,cardiovascular disease,and chronic kidney disease,and discusses the definition and naming of CKM,aiming to offer practical guidance for clinical practice.

关 键 词：心血管-肾脏-代谢综合征 代谢综合征 肥胖症 糖尿病 

分 类 号：R589[医药卫生—内分泌]