滑液囊支原体疫苗研究进展  

Research progress on Mycoplasmopsis synoviae vaccine

作　　者：邓兰兰 张文婷 胡巧 郭云清 曹晓怡 廖卫东 张腾飞[2] 翟新国 罗青平[2,3] DENG Lanlan;ZHANG Wenting;HU Qiao;GUO Yunqing;CAO Xiaoyi;LIAO Weidong;ZHANG Tengfei;ZHAI Xinguo;LUO Qingping(College of Life Science and Food Engineering,Hebei University of Engineering,Handan 056000,China;Ministry of Agriculture and Rural Affairs Key Laboratory of Preparation Creation for the Prevention and Control of Livestock and Poultry Bacterial Diseases/Hubei Provincial Key Laboratory of Livestock and Poultry Pathogenic Microbiology,Institute of Animal Husbandry and Veterinary Medicine,Hubei Academy of Agricultural Sciences,Wuhan 430064,China;Hubei Hongshan Laboratory,Wuhan 430070,China)

机构地区：[1]河北工程大学生命科学与食品工程学院,河北邯郸056000 [2]湖北省农业科学院畜牧兽医研究所农业农村部畜禽细菌病防治制剂创制重点实验室/畜禽病原微生物学湖北省重点实验室,武汉430064 [3]湖北洪山实验室,武汉430070

出　　处：《黑龙江畜牧兽医》2024年第23期6-11,共6页Heilongjiang Animal Science And veterinary Medicine

基　　金：湖北省技术创新计划项目“禽支原体病绿色高效防控技术研发”(2024BBB074);国家肉鸡产业技术体系项目(CARS-41);湖北省自然科学基金重点类项目(2021CFA019);湖北省第四批现代农业产业技术体系禽蛋产业技术体系项目(2023HBSTX4-04)。

摘　　要：滑液囊支原体(Mycoplasma synoviae,MS)是重要的禽类致病性支原体之一,感染家禽后主要引起关节和脚垫肿胀、上呼吸道感染,造成产蛋率下降、蛋壳顶端异常(EAA)、饲料转化率下降、淘汰率上升等,给我国养禽业造成了不可估量的经济损失。使用MS疫苗免疫接种是预防该病的重要措施。文章综述了MS弱毒活疫苗、灭活疫苗和基因工程亚单位疫苗的研究进展,以期为研究高保护效果的MS疫苗提供参考。Mycoplasmopsis synoviae(MS)is one of the important avian pathogenic Mycoplasma.Infection in poultry mainly causes swollen joints and foot pads,subclinical upper respiratory tract infection,and results in a decrease in egg laying rate,abnormal eggshell tip(EAA),decrease in feed conversion rate,and increase in elimination rate.It has caused immeasurable economic losses to China's poultry industry.Immunization with the MS vaccine is an important measure to prevent the disease.This article reviewed the research progress of live attenuated MS vaccines,inactivated vaccines and genetically engineered subunit vaccines,in order to provide a reference for the study of MS vaccines with high protective effect.

关 键 词：滑液囊支原体 弱毒活疫苗 灭活疫苗 基因工程亚单位疫苗 免疫接种 

分 类 号：S858.31[农业科学—临床兽医学] R375.3[农业科学—兽医学]