亚甲蓝混合液应用于肛肠疾病术后的研究进展  

Research Progress on the Application of Methylene Blue Mixture in Postoperative Anal and Rectal Diseases

作　　者：张建华 李鹏 李德[1] 郭强 左国富 闫平 郝建国[1] 张铭正 ZHANG Jianhua;LI Peng;LI De;GUO Qiang;ZUO Guofu;YAN Ping;HAO Jianguo;ZHANG Mingzheng(Department of Anorectal Surgery,Taiyuan Central Hospital(Peking University First Hospital Taiyuan Hospital),Taiyuan,Shanxi 030001,China)

机构地区：[1]太原市中心医院(北京大学第一医院太原医院)肛肠外科,山西太原030001

出　　处：《中国医药指南》2025年第1期61-64,共4页Guide of China Medicine

基　　金：太原市科学技术局项目(202249)。

摘　　要：肛肠疾病是临床上的常见病,手术治疗是目前重要的治疗手段,但术后疼痛是其术后的常见并发症之一,这给患者的术后康复造成了巨大影响。因此将患者的疼痛感尽量降低或者无痛是肛肠手术面临的一大难题。本文将亚甲蓝混合液借助注射法应用于痔、肛周脓肿、肛瘘及肛裂等肛肠疾病术后,发现其具有良好的镇痛效果。亚甲蓝混合液是一种由亚甲蓝注射液、局部麻醉剂以及生理盐水等组成的混合液。但是,亚甲蓝具有一定潜在毒性和过敏反应等问题,临床上使用时还需谨慎。未来研究需要进一步探讨亚甲蓝在不同肛肠手术类型中的最优使用方案、剂量浓度以及与其他治疗方法联合应用的效果。Proctology is a common clinical disease,and surgical treatment is currently an important treatment method.However,postoperative pain is one of the common complications,which has a huge impact on the postoperative recovery of patients.Therefore,minimizing or avoiding pain for patients is a major challenge in anal surgery.This article applies methylene blue mixed solution through injection method to postoperative anal and rectal diseases such as hemorrhoids,perianal abscess,anal fistula,and anal fissure,and finds that it has a good analgesic effect.Methylene blue mixture is a type of mixture that is prepared in a certain proportion from methylene blue injection,local anesthetic,and physiological saline.However,methylene blue has certain potential toxicity and allergic reactions,and caution should be exercised when using it in bed.Future research needs to further explore the optimal use plan,dosage concentration,and combined effect with other treatment methods of methylene blue in different types of anal and rectal surgeries.

关 键 词：肛肠疾病 术后疼痛 亚甲蓝 镇痛 

分 类 号：R657.1[医药卫生—外科学]