内切脂肪回填泪沟和内入路眶膈脂肪重置两种术式在眼袋手术中应用的meta分析  

Meta-analysis of the Application of Internal Fat Backfilling of Lacrimal Furrows and Internal Approach of Orbital Diaphragm Fat Replacement in Pouch Surgery

作　　者：覃科杰 张金明[1] Kejie Qin;Jinming Zhang(Department of Plastic and Reconstruction Surgery,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guang-)

机构地区：[1]中山大学孙逸仙纪念医院整形外科,广东广州510120

出　　处：《医学研究前沿》2024年第8期30-34,共5页Frontiers of Medical Research

摘　　要：目的目的采用Meta分析法,对内切法填充泪沟及内入路眶隔脂肪重置术治疗下睑袋的疗效及安全性进行了评价。方法方法使用中国生物医学文献数据库(CBM)、中国图书馆(CNKI)、中国万方(万方)、中文科学杂志(Wikipedia)、PubMed(PubMed)、《科学》(Webof Science)、Cochrane图书馆(Cochrane Library)收集建库至2023年6月30日。内切脂肪回填泪沟和内入路眶膈脂肪重置两种术式在眼袋手术中应用的随机对照试验(RCT),本研究使用Cochrane5.1.0偏倚风险评估工具和Rev-Man5.3的Meta分析来评估所选的文章的质量。结果共收集了352个样本,共8篇相关文章。结果结果内切脂肪回填泪沟和内入路眶膈脂肪重置两种术式在眼袋手术中应用的总有效率相当(OR=0.937,95%CI[0.907,0.958],P=0.91),内入路眶膈脂肪重置的泪沟畸形等级量表(Tear trough rating scale,TTRS)评分(MD=1.620,95%CI[1.572,1.668],P<0.01)显著低于内切脂肪回填泪沟组。两种术式的手术并发症差异没有统计学意义(OR=0.071,95%CI[0.048,0.103],P=0.12)。结论内切脂肪回填泪沟和内入路眶膈脂肪重置两种术式在眼袋手术中应用的疗效相当,而内入路眶膈脂肪重置术式在改善泪沟畸形方面更有优势,且并发症少,具有较高的临床推广价值。Objective The efficacy and safety of lacrimal furrows filled with internal incision and orbital septal fat reconstruction in the treatment of lower eyelid pouch were evaluated by Meta analysis.Method Chinese Biomedical Literature Database(CBM),Chinese Library(CNKI),China Wanfang(Wanfang),Chinese Science journal(Wikipedia),PubMed(PubMed),Webof Science,Cochrane Library(Cochrane)were used Library until June 30,2023.A randomized controlled trial(RCT)of intraoperative fat backfilling of lacrimal trench and intraap-proach orbital diaphragm fat replacement in pouch surgery.The Cochrane5.1.0 bias risk assessment tool and RevMan5.3 meta-analysis were used to evaluate the quality of the selected articles.Result A total of 8 literatures were included,with a total sample size of 352 cases.The results of meta-analysis showed that the total effective rates of internal fat backfilling of lacrimal groove and internal approach orbital diaphragm fat replacement in pouch surgery were comparable(OR=0.937,95%CI[0.907,0.958],P=0.91).The Tear trough rating scale(TTRS)score of intraapproach orbital phrenic fat replacement(MD=1.620,95%CI[1.572,1.668],P<0.01)was significantly lower than that of the intraapproach orbital phrenic fat backfilling group.There was no significant difference in surgical complications between the two methods(OR=0.071,95%CI[0.048,0.103],P=0.12).Conclusion The internal fat filling of lacrimal furrows and the internal approach of orbital diaphragm fat replacement have the same efficacy in pouch surgery,while the internal approach of orbital diaphragm fat replace-ment has more advantages in improving lacrimal furrows with fewer complications,and has high clinical promotion value.

关 键 词：内切脂肪回填泪沟 内入路眶膈脂肪重置 眼袋手术 META分析 有效性 

分 类 号：R62[医药卫生—整形外科]