医学论文写作中的设计缺陷及统计学问题分析  

Analysis of design flaws and statistical issues in manuscripts submitted to core medical journals

作　　者：余诗诗 吴锦雅 经媛 陈望忠 孙昌朋 YU Shi-shi;WU Jin-ya;JING Yuan;CHEN Wang-zhong;SUN Chang-peng(Editorial Department of the Journal of Southern Medical University,Guangzhou 510515,Guangdong,China)

机构地区：[1]南方医科大学学报编辑部,广东广州510515

出　　处：《现代预防医学》2024年第24期4597-4602,共6页Modern Preventive Medicine

基　　金：广东省科学技术厅课题-广东省科技期刊优秀人才项目(2024B1212110007),中国科技期刊卓越行动计划项目(卓越计划-C-081)。

摘　　要：目的分析向国内核心期刊投稿的医学论文中存在的设计缺陷及统计学问题,探索提高医务人员和医学生论文质量和投稿命中率的策略。方法问卷调查收集2021年1月至2023年12月国内医学核心期刊稿件内容,进行定量实证和定性分析。结果纳入分析306篇临床医学研究论文和328篇基础医学研究论文,录用率差异有统计学意义(P<0.001),不同基金级别稿件的录用率差异无统计学意义(P>0.05)。观察性研究占全部稿件的71.40%,但其录用率低于实验性研究(43.75%vs.53.66%,P<0.05)。稿件在方法学设计和统计学分析报告方面存在多种缺陷,主要问题包括:研究设计类型表述不清、组间匹配不严谨、建模和验证不足、忽略样本量计算、结果报告错误。结论医学稿件在研究设计和统计分析报告方面存在显著缺陷,与国际通用的医学报告规范存在较大差距。医院和医科院校应加强对最新医学研究规范和统计学知识培训,以提升学术论文质量,增加科研论文成果。Objective To analyze the design flaws and statistical issues present in medical papers submitted to core domestic journals,and to explore strategies for improving the quality of medical papers and submission acceptance rates.Methods A questionnaire survey was conducted to collect data on submissions to domestic core medical journals between January 2021 and December 2023.Quantitative empirical and qualitative analyses were performed.Results A total of 306 clinical medicine research papers and 328 basic medicine research papers were included in the analysis.There was a statistically significant difference in the acceptance rates between these two categories(P<0.001),while no significant difference was found concerning the acceptance rates of papers supported by different levels of funding(P>0.05).Observational studies constituted 71.40%of all submissions;however,their acceptance rate was lower than that of experimental studies(43.75%vs.53.66%,P<0.05).Various deficiencies were identified in the methodological design and statistical analysis reporting of the manuscripts.The main issues included unclear description of study design types,inadequate matching between groups,insufficient modeling and validation,neglect of sample size calculation,and errors in result reporting.Conclusion Significant flaws exist in the research design and statistical analysis reporting of medical manuscripts,with a considerable gap compared to internationally recognized medical reporting standards.Hospitals and medical schools should strengthen training in the latest medical research standards and statistical knowledge to improve the quality of academic papers and enhance research outcomes.

关 键 词：医学论文质量 研究设计缺陷 统计学问题 录用率 研究报告规范 

分 类 号：R195.1[医药卫生—卫生统计学]