一例仔猪蓝耳病毒与细菌混合感染的诊治  

Diagnosis and treatment of mixed infection of porcine reproductive and sespiratory syndrome virus and bacteria

作　　者：鲁绪文 谭伟明 张寄香 王贵平[1] LU Xuwen;TAN Weiming;ZHANG Jixiang;WANG Guiping(College of Veterinary Medicine,Hunan Agricultural University,Changsha Hunan 410128;Yiyang Vocational and Technical College,Yiyang Hunan 413000)

机构地区：[1]湖南农业大学动物医学院,湖南长沙410128 [2]益阳职业技术学院,湖南益阳413000

出　　处：《现代牧业》2024年第3期29-33,共5页Modern Animal Husbandry

摘　　要：湖南省益阳市某养猪场仔猪出现发烧、呼吸急促以及咳嗽等临床症状。经剖检,发现病猪出现腹股沟淋巴结肿大和肺水肿等病变。为尽快对仔猪所患疾病进行确诊以便采取有效的防治措施,采集病猪的肺、肝、肾和肠系膜淋巴结,进行猪蓝耳病毒、猪圆环病毒(2型)、奇异变形杆菌、粪肠球菌及大肠杆菌的qPCR检测、细菌分离培养鉴定及药敏试验。结果显示,样品的猪蓝耳病毒qPCR检测为阳性,猪圆环病毒(2型)为阴性。病原菌的分离鉴定及药敏试验结果表明,分离得到奇异变形杆菌、粪肠球菌及大肠杆菌三株致病菌;三种菌均对多粘菌素B、呋喃唑酮和万古霉素敏感。本次病例检测结果说明,仔猪是在感染猪蓝耳病毒后继发感染多种细菌引起疾病的,防控首选药物为多粘菌素B、呋喃唑酮或万古霉素,猪场应加强疫苗免疫工作。本研究为该场仔猪细菌性呼吸道感染的防控提供理论基础。Piglets from a pig farm in Yiyang City,Hunan Province showed fever,shortness of breath and cough.The pathological changes of inguinal lymph node enlargement and pulmonary edema were found.In order to confirm the disease in the pig farm as soon as possible and take effective control measures,the lung,liver,kidney and mesenteric lymph nodes of the infected pigs were collected,and the qPCR detection,isolation culture identification and drug susceptibility test of porcine reproductive and sespiratory syndrome virus(PRRSV),porcine circovirus type 2(PCV2),Proteus mirabilis,Enterococcus faecalis and Escherichia coli were carried out.The results showed that PRRSV was positive by qPCR and PCV2 was negative.The isolation and identification of pathogenic bacteria and the results of drug susceptibility test showed that three pathogenic bacteria,Proteus mirabilis,Enterococcus faecalis and Escherichia coli were isolated;all three strains were sensitive to polymyxin B,furazolidone and vancomycin.The test results of this case showed that piglets are infected with PRRSV after the secondary infection of a variety of bacteria caused disease,the first drug for prevention and control was polymyxin B,furazolidone or vancomycin,pig farms should strengthen vaccine immunization work.This study provided a theoretical basis for the prevention and control of bacterial respiratory tract infection of piglets in this farm.

关 键 词：断奶仔猪 蓝耳病毒 药敏试验 继发感染 

分 类 号：S851.3[农业科学—预防兽医学]