异位妊娠与生殖道病原体感染的相关性研究  

Study on the correlation between ectopic pregnancy and reproductive tract pathogen infection

作　　者：付玉娇 石日玲 蓝爱琴[1] 蔡健[1] 陈艳艳 FU Yu-jiao;SHI Ri-ling;LAN Ai-qin;CAI Jian;CHEN Yan-yan(Beihai People's Hosptial,Beihai 536000,China)

机构地区：[1]北海市人民医院,北海市536000

出　　处：《妇产与遗传（电子版）》2024年第1期20-22,共3页Obstetrics-Gynecology and Genetics (Electronic Edition)

摘　　要：目的 探讨生殖道病原体感染与异位妊娠(Ectopic pregnancy,EP)的相互关系,降低异位妊娠的再次出现。方法 采用回顾性分析,选取2023年1月至2023年12月于北海市人民医院门诊就诊有EP病史的患者69例为观察组,取同期门诊就诊正常妊娠史患者69例为对照组,分别取其宫颈管分泌物行解脲脲原体(Ureaplasma urealyticum,UU)、沙眼衣原体(Chlamydia trachomatis,CT)以及淋病奈瑟球菌(Neisseria gonorrhoeae,NG) DNA检测。结果 观察组UU感染率为52.17%(阳性者36例)、CT感染率为5.80%(阳性者4例),分别高于对照组的UU感染率27.54%(阳性者19例)、CT感染率1.45%(阳性者1例),两组的NG感染率均为0.00%。两组之间的UU感染率有显著差异,有统计学意义(P=0.003)。结论 生殖道UU感染与EP的发生密不可分。孕前生殖道病原体的检测以及足够疗程的抗生素应用是降低EP发生的关键。Objective To explore the correlation between reproductive tract pathogen infection and ectopic pregnancy(EP),and to reduce the incidence rate of ectopic pregnancy.Methods 69 EP patients received treatment in Beihai Peoples Hospital from January 2023 to December 2023 were retrospectively analyzed as the observation group,and 69 patients with a history of normal pregnant in the outpatient clinic during the same period were analyzed as the control group.The DNA tests of cervical secretions were performed in the two groups for the detection of ureaplasma urealyticum(UU),chlamydia trachomatis(CT)and neisseria gonorrhoeae(NG).Results The UU infection rate of the observation group was 52.17%(36 positive cases)and the CT infection rate was 5.8%(4 positive cases),which were higher than the UU infection rate of the control group which was 27.54%(19 positive cases)and the CT infection rate of 1.45%(1 positive case),respectively,and the NG infection rate of both group was 0.00%(0 case ofpositive).There was a statistically significant difference in UU infection rate between the two groups(P=0.003).Conclusions Genital tract UU infection was closely associated withthe development of EP.Pre‐pregnancy testing for reproductive tract pathogens and adequate courses of antibiotics could help to reduce the incidence of EP.

关 键 词：异位妊娠 解脲脲原体 沙眼衣原体 淋病奈瑟球菌 

分 类 号：R714.22[医药卫生—妇产科学]