基于纽曼系统干预模式下高压氧治疗对NSTEMI患者心肌功能、健康行为及预后的影响  

Impacts of hyperbaric oxygen therapy on myocardial function,health behavior and prognosis in NSTEMI patients based on the intervention mode of Newman system

作　　者：刘青[1] 金爱莲[1] 李帅[1] 郭琦 Liu Qing;Jin Ailian;Li Shuai;Guo Qi(Cardiovascular Intensive Care Unit,The First People’s Hospital of Shangqiu,Shangqiu 476000,China;Department of Hyperbaric Oxygen,The First People’s Hospital of Shangqiu,Shangqiu 476000,China)

机构地区：[1]商丘市第一人民医院心脏重症监护室,商丘476000 [2]商丘市第一人民医院高压氧科,商丘476000

出　　处：《中华航海医学与高气压医学杂志》2024年第6期791-795,共5页Chinese Journal of Nautical Medicine and Hyperbaric Medicine

摘　　要：目的探讨基于纽曼系统干预模式下高压氧治疗对非ST段抬高型心肌梗死(NSTEMI)患者心肌功能、健康行为及预后的影响。方法选取2022年1月至2023年1月商丘市第一人民医院心血管内科收治的89例NSTEMI中高危层级患者作为研究对象。按照治疗方法将患者分为对照组(n=47)和研究组(n=42)。对照组采用纽曼系统干预模式联合常规治疗,研究组在常规治疗基础上选择纽曼系统干预模式联合高压氧治疗。采用单光子发射计算机断层成像仪分析并计算代谢摄取分数(99mTc-MIBI);采用全自动生化分析仪检测血清心肌肌钙蛋白Ⅰ(cTnⅠ)、肌酸激酶同工酶(CK-MB)水平;利用二维超声心动图测量左室收缩末期内径(LVESD)、左室舒张末期内径(LVEDD),并计算左室摄血分数(LVEF);采用健康促进生活方式量表Ⅱ(HPLP-Ⅱ)评价2组患者治疗前后的健康行为;统计2组患者治疗过程中心血管不良事件发生情况。结果与治疗前比较,研究组患者治疗后99 mTc-MIBI摄取分数明显提高(P<0.01),治疗后研究组99mTc-MIBI摄取分数明显高于对照组(P<0.01)。治疗后研究组血清cTnⅠ、CK-MB水平均明显低于对照组(P<0.05或P<0.01),LVEF明显高于对照组(P<0.01),LVESD、LVEDD明显小于对照组(P<0.05)。与治疗前比较,2组患者治疗后HPLP-Ⅱ各因子评分均明显升高,且治疗后研究组患者明显高于对照组(P<0.01)。对照组患者心血管不良事件发生率(14.89%)明显高于研究组(2.38%),差异有统计学意义(χ^(2)=4.245,P=0.039)。结论纽曼系统干预模式联合高压氧治疗可促进NSTEMI患者心肌功能恢复,提高健康行为,改善预后,且安全性较高。Objective To explore the effects of hyperbaric oxygen therapy based on the intervention mode of Newman system on myocardial function,health behavior,and prognosis in patients with non-ST segment elevation myocardial infarction(NSTEMI).Methods A total of 89 NSTEMI patients at medium and high risk levels admitted to the Cardiovascular Department of the First People’s Hospital of Shangqiu from January 2022 to January 2023 were selected as the study subjects.The patients were divided into a control group(n=47)and a study group(n=42)according to their treatment methods.The control group received conventional treatment combined with the intervention mode of Newman system,while the study group received the intervention mode of Newman system combined with hyperbaric oxygen therapy on the basis of conventional treatment.The metabolic uptake fraction(99mTc-MIBI)was analyzed and calculated using a single photon emission computed tomography;a fully automated biochemical analyzer was used to detect serum levels of cardiac troponinⅠ(cTnⅠ)and creatine kinase isoenzyme(CK-MB);left ventricular end systolic diameter(LVESD)and left ventricular end diastolic diameter(LVEDD)were measured using two-dimensional echocardiography,and left ventricular ejection fraction(LVEF)was calculated;the health behavior of two groups of patients before and after treatment was evaluated using the Health Promotion Lifestyle InventoryⅡ(HPLP-Ⅱ);the incidence of cardiovascular adverse events during treatment in two groups of patients was statistically analyzed.Results Compared with before treatment,the study group showed a significant increase in 99mTc-MIBI uptake fraction after treatment(P<0.01);and the 99mTc-MIBI uptake fraction in the study group after treatment was significantly higher than that in the control group(P<0.01).After treatment,the levels of cTnI and CK-MB in the study group were significantly lower than those in the control group(P<0.05 or P<0.01),and LVEF in the study group was significantly higher than that in the control grou

关 键 词：非ST段抬高型心肌梗死 纽曼系统干预模式 高压氧 心肌功能 健康行为 

分 类 号：R542.22[医药卫生—心血管疾病] R459.6[医药卫生—内科学]