病毒性肺炎患者T淋巴细胞亚群变化的研究意义  

Research on Significance of Changes in T Lymphocyte Subsets in Patients with Viral Pneumonia

作　　者：韩妤 刘晖[1] HAN Yu;LIU Hui(The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830000,China)

机构地区：[1]新疆医科大学第一附属医院,新疆乌鲁木齐830000

出　　处：《工业微生物》2024年第6期7-9,共3页Industrial Microbiology

摘　　要：病毒性肺炎(viral pneumonia)是由病毒侵入上呼吸道上皮及肺泡上皮细胞引起的肺实质和间质炎症。免疫应答在抑制病毒感染的过程中发挥着重要的作用。然而,免疫反应是一把“双刃剑”,一方面,可能会加速病毒的清除,促进身体恢复;另一方面,机体过度的免疫应答激活也可能会加重炎症反应,引发炎症因子风暴,严重时还可能并发急性呼吸窘迫综合征和多器官功能衰竭,甚至导致死亡。全面认识病毒性肺炎患者的T淋巴细胞变化,可能会对疾病诊断、病情及预后评估产生重要作用。Viral pneumonia is the lung parenchymal and interstitial inflammation caused by the viral invasion into the upper respiratory tract epithelium and alveolar epithelial cells.The immune response plays an important role in suppressing viral infection.However,the immune response is a“double-edged sword”.On the one hand,it may accelerate the removal of the virus and promote the recovery of the body.On the other hand,the excessive activation of the immune response may aggravate the inflammatory response,and lead to the cytokine storm.In severe cases,it also may be complicated by acute respiratory distress syndrome and multiple organ failure,and even lead to death.A comprehensive understanding of T lymphocyte changes in patients with viral pneumonia may play an important role in disease diagnosis,disease condition and prognosis assessments,and other aspects.

关 键 词：病毒性肺炎 淋巴细胞亚群 肺泡灌洗液 

分 类 号：R563.1[医药卫生—呼吸系统]