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作 者:柴德建 蔡卓昊 田露[2] CHAI Dejian;CAI Zhuohao;TIAN Lu(Graduate School of Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;College of Traditional Chinese Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China)
机构地区:[1]天津中医药大学研究生院,天津301617 [2]天津中医药大学中医学院,天津301617
出 处:《中国性科学》2024年第12期110-114,共5页Chinese Journal of Human Sexuality
基 金:天津市卫生健康委中医古籍文献收集整理项目(ZX2021021);中医“治未病”理论与辨识应用研究项目(XJ201801);中医慢病临床科研体系及其成果转化应用模式研究项目(201107006)。
摘 要:目的运用数据挖掘技术,从多层次、多角度探寻有清名医江涵暾在《笔花医镜》中治疗女科疾病的处方用药特色。方法筛选《笔花医镜》中治疗女科疾病的方剂并建立数据库,借助中医传承辅助平台V3.0软件进行统计、药物频次、关联规则及聚类分析。结果共纳入处方90首,药物共计125味。累计用药频次670次,以补虚、活血化瘀、理气及利水渗湿类药物为主,处方中频次前10位中药为当归、甘草、川芎、白术、茯苓、人参、白芍、地黄、大枣、生姜;药物性味以甘温之品使用频率最高,药物归经以脾经最多,其次是心肝肺等;药物关联规则共23组,频度靠前的为川芎、白芍→当归,大枣→甘草等;聚类分析得到以当归为核心的3首聚类方。结论江涵暾对女科疾病的诊疗,论治重调血气,兼以利水祛湿;用药味甘苦辛,注重温补血脉;强调脾心肝肺四经。Objective To explore the characteristics of prescription medication in the treatment of gynecological diseases in Bi Hua Yi Jing by Jiang Hantun,a renowned doctor from multiple levels and perspectives using data mining technology.Methods The prescriptions for treating gynecological diseases in Bi Hua Yi Jing were screened to establish a database.Statistical,drug frequency,association rules,and clustering analysis were conducted using the traditional Chinese medicine inheritance assistance platform V3.0 software.Results A total of 90 prescriptions were included,with a total of 125 drugs.The cumulative frequency of medication was 670 times,mainly focusing on drugs of tonifying deficiency,promoting blood circulation and removing stasis,regulating Qi,and promoting diuresis and dampness.The Chinese herbal medicines with the top 10 frequency in the prescriptions were angelica sinensis,licorice,ligusticum wallichii,atractylodes macrocephala,poria cocos,ginseng,white peony,rehmannia glutinosa,jujube,and ginger.Among medicinal properties and tastes,the frequency of using sweet and warm medicinal products was the highest,with the spleen meridian being the most common medicinal meridian,followed by the heart,liver,and lungs.There were 23 groups of drug association rules,with the most frequent ones being ligusticum wallichii,white peony→angelica sinensis,jujube→licorice,etc.Clustering analysis yielded three clustering prescriptions with angelica sinensis as the core.Conclusions The diagnosis and treatment of gynecological diseases by Jiang Hantun focus on regulating blood and Qi,as well as promoting diuresis and dispelling dampness.The medicinal taste is sweet,bitter,and spicy,with a focus on warming and tonifying the blood vessels,with the four meridians of spleen,heart,liver,and lung emphasized.
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