基于肠道菌群探讨从肝脾肾论治疗卵巢早衰  

Exploration on the treatment of premature ovarian failure from the perspective of liver,spleen and kidney based on intestinal flora

作　　者：黎玲 金志春 叶朝阳[1,2] 王珺[3] LI Ling;JIN Zhichun;YE Zhaoyang;WANG Jun(School of Traditional Chinese Medicine,Hubei University of Chinese Medicine,Wuhan 430065,Hubei,China;Department of Reproductive,Maternal and Child Health Hospital of Hubei Province,Wuhan 430070,Hubei,China;the First School of Clinical Medicine,Hubei University of Chinese Medicine,Wuhan 430065,Hubei,China)

机构地区：[1]湖北中医药大学中医学院,武汉430065 [2]湖北省妇幼保健院生殖科,武汉430070 [3]湖北中医药大学第一临床学院,武汉430065

出　　处：《中国性科学》2024年第12期131-134,共4页Chinese Journal of Human Sexuality

摘　　要：卵巢早衰(POF)指女性在40岁之前由于多种原因导致卵巢功能提前减退,其发病机制尚不明确。有研究显示,肠道菌群通过多渠道、多靶点影响POF的发生和发展,同时也有研究显示,临床可通过调理肝脾肾改善肠道菌群功能。目前,关于调理肝脾肾改善肠道菌群是否可以延缓卵巢衰老的相关研究较少。因此,本课题组提出以肠道菌群失调为桥梁,探讨从肝脾肾论治疗POF,从而发掘中医调理肝脾肾改善POF的新机制。Premature ovarian failure(POF)refers to the premature decline of ovarian function in women before the age of 40 due to various reasons,with unclear pathogenesis.There were studies shown that intestinal flora affects the occurrence and development of POF through multiple channels and multiple targets,while some studies revealed that the function of intestinal flora can be improved by regulating liver,spleen and kidney in clinic.At present,there is little research on whether regulating liver,spleen and kidney to improve intestinal flora can delay ovarian aging.Therefore,this research puts forward to explore the treatment of POF from the theory of liver,spleen and kidney by taking intestinal flora imbalance as a bridge,so as to explore the new mechanism of regulating liver,spleen and kidney to improve POF in traditional Chinese medicine.

关 键 词：卵巢早衰 肠道菌群 肝脾肾 

分 类 号：R711[医药卫生—妇产科学]