高弹海绵填塞离心杯提高血液成分制备一次成浆率的方法研究  

Study on the method of improving the primary slurry rate of blood component preparation by filling centrifugal cup with high-elastic sponge

作　　者：王小芹 王欣若 汤蓉蓉 WANG Xiaoqin;WANG Xinruo;TANG Rongrong(Blood Center of Nantong,Jiangsu,Nantong 226007,China;School of Life Science,Nantong University,Jiangsu,Nantong 226019,China)

机构地区：[1]江苏省南通市中心血站,江苏南通226007 [2]南通大学生命科学学院,江苏南通226019

出　　处：《中国医药科学》2024年第23期173-176,共4页China Medicine And Pharmacy

基　　金：江苏省南通市卫生健康委员会科研课题(MS2022097)。

摘　　要：目的探讨高弹海绵填塞离心杯离心对提高一次成浆率的效果。方法随机抽取南通市中心血站2022年8—12月采集的保存于2~6℃当天制备的无偿献血者血液,在滤除白细胞后血袋配平,实验组装入离心杯后用高弹海绵填塞后离心,对照组未使用高弹海绵填塞离心。比较两组一次成浆率及离心破损的差异。结果实验组一次成浆率为98.33%,明显高于对照组的90.53%,差异有统计学意义(χ^(2)=105.800,P<0.05)。实验组300 ml和400 ml血液一次成浆率分别为98.07%和98.56%,均较对照组有明显提高,差异有统计学意义(χ^(2)=59.316,P<0.05;χ^(2)=34.388,P<0.05)。两组离心破损渗漏率比较,差异无统计学意义(χ^(2)=2.409,P>0.05)。结论应用高弹海绵填塞离心杯离心,可有效改善血袋离心过程中出现的折皱、塌陷、红细胞贴壁等问题,明显提高血液一次成浆率。Objective To explore the effect of filling centrifugal cup with high-elastic sponge on improving the primary slurry rate.Methods The blood of voluntary blood donors collected from Blood Center of Nantong from August to December 2022 and stored at 2-6℃was randomly selected,and the blood bags were balanced after leucocytes were filtered.After the experiment was assembled into a centrifuge cup,it was filled with high-elastic sponge and centrifuged.The control group did not use high-elastic sponge to fill and centrifuge.The differences of primary slurry rate and centrifugal damage between the two groups were compared.Results The primary slurry rate in the experimental group was 98.33%,which was significantly higher than that in the control group(90.53%),and the difference was statistically significant(χ^(2)=105.800,P<0.05).The primary slurry rate of 300 ml and 400 ml blood in the experimental group were 98.07%and 98.56%,respectively,which were significantly higher than those in the control group(χ^(2)=59.316,P<0.05.χ^(2)=34.388,P<0.05).There was no significant difference in the centrifugal breakage leakage rate between the two groups(χ^(2)=2.409,P>0.05).Conclusion Using filling centrifugal cup with high-elastic sponge for centrifugation can effectively improve the problems such as wrinkling,collapse and red blood cells adhesion during the centrifugation of blood bags,obviously improve the primary slurry rate of blood.

关 键 词：高弹海绵 填塞离心 一次成浆率 血液制备 

分 类 号：R457.1[医药卫生—治疗学]