光电化学生物传感器检测重金属铅离子的研究进展  

Research progress of photoelectrochemical biosensors in heavy metal lead ions detection

作　　者：陈杨 王佳鹏 周游 石帅晨 晏致涛 李孟洁 Chen Yang;Wang Jia-peng;Zhou You;Shi Shuai-chen;Yan Zhi-tao;Li Meng-jie(School of Civil and Hydraulic Engineering,Chongqing University of Science&Technology,Chongqing 401331,China)

机构地区：[1]重庆科技大学土木与水利工程学院,重庆401331

出　　处：《化学传感器》2024年第2期26-33,共8页Chemical Sensors

基　　金：重庆科技大学硕士研究生创新计划项目(YKJCX2220608);重庆科技大学新教师研究启动基金项目(CKRC202024);重庆市教育委员会科学技术研究项目(KJQN202101522)。

摘　　要：铅离子(Pb^(2+))是一种广泛存在的有毒金属污染物,严重威胁着人类的健康。因此,开发高效、灵敏检测Pb^(2+)的方法具有重要意义。光电化学(PEC)生物传感器具有高选择性和高灵敏度等优点,已被广泛应用于环境监测、医学研究及食品安全分析等领域。该文分三种类型综述了用于Pb^(2+)检测的PEC生物传感器:(1)材料直接识别Pb^(2+)的PEC生物传感器;(2)Pb^(2+)依赖性脱氧核酶(DNAzyme)型PEC生物传感器;(3)G-四链体型PEC生物传感器。这些对Pb^(2+)具有高灵敏度和强特异性的PEC生物传感器,在未来真实环境和实时生物样品的检测中有望成为实际应用的工具。Lead ions(Pb^(2+))are a widely occurring toxic metal pollutant that seriously threatens human health.Therefore,it is of great significance to develop efficient and sensitive methods for detecting Pb^(2+).Photoelectrochemical(PEC)biosensors possess the advantages of high selectivity and sensitivity,which has been widely used in the fields of environmental monitoring,medical research and food safety analysis.This paper reviews the application of PEC biosensors in Pb^(2+)detection:(1)PEC biosensor based on direct recognition between material and Pb^(2+);(2)Pb^(2+)-dependent deoxyribonuclease(DNAzyme)type PEC biosensor;(3)G-quadruplex type PEC biosensor.These PEC biosensors for Pb^(2+)analysis with high sensitivity and strong specificity are expected to become practical tools in the detection of real environments and real-time biological samples in the future.

关 键 词：光电化学 生物传感器 重金属 铅离子 

分 类 号：O657.1[理学—分析化学] TP212.3[理学—化学]