Biocompatibility of Morphology on Laser-Processed Magnesium Alloy Surfaces  

激光加工镁合金表面形貌的生物相容性

作　　者：Liu Peng Guo Xuan Gao Dongfang Zhao Yangyang Qiao Yang 刘鹏;郭璇;高冬芳;赵洋洋;乔阳(济南大学机械工程学院,山东济南250022;山东省青岛市市北区教育和体育局,山东青岛266022;山东大学第二医院基础医学研究所,山东济南250033;山东大学第二医院创伤骨科,山东济南250031)

机构地区：[1]School of Mechanical Engineering,University of Jinan,Jinan 250022,China [2]Shibei District of Education and Sports Bureau,Qingdao of Shandong Province,Qingdao 266022,China [3]Institute of Basic Medical Sciences,The Second Hospital of Shandong University,Jinan 250033,China [4]Traumatic&Orthopedics Department,The Second Hospital of Shandong University,Jinan 250031,China

出　　处：《稀有金属材料与工程》2024年第12期3321-3328,共8页Rare Metal Materials and Engineering

基　　金：Shandong Provincial Natural Science Foundation(ZR2023ME077,ZR2023MC140);National Natural Science Foundation of China(52175408)。

摘　　要：The surface of magnesium alloy was laser-processed,and the laser-etched morphology was determined as grooves by observing the surface morphology of sheep rib bone.The wettability of different morphologies was investigated by contact angle test.Through the cell adhesion test,the effects of different morphologies on cell adhesion,growth and migration were investigated.Results show that the wetting angle of the block-shaped surface is smaller than that of the groove-shaped surface,and block-shaped surface has better hydrophilicity.Compared with the smooth surface,the block-shaped surface has better cell adhesion,and the depressions and bumps are full of cells,suggesting that the micropatterns prepared by the laser processing are conducive to the enhancement of biocompatibility.对镁合金表面进行激光加工改性,通过观察羊肋骨表面形貌,确定激光刻蚀形貌为沟槽。通过接触角测试,探究镁合金表面不同形貌的润湿性。通过细胞粘附试验,探究不同形貌的镁合金表面对细胞粘附、生长、迁移的影响。结果表明,田形形貌润湿角比沟槽形貌小,田形形貌的镁合金表面有更好的亲水性;与光滑表面相比,田形表面细胞附着性好,凹陷及凸起处均铺满细胞,这说明经过激光加工处理获得的显微图案有利于生物相容性的提高。

关 键 词：magnesium alloy laser surface modification BIONIC WETTABILITY cell adhesion 

分 类 号：TG665[金属学及工艺—金属切削加工及机床] TG146.22[一般工业技术—材料科学与工程]