某种新型复方消毒剂对鼠疫菌及炭疽芽孢杆菌的消毒效果评价  

Evaluation of a new compound disinfectant for Yersinia pestis and Bacillus anthracis disinfection

作　　者：张海鹏[1] 彭海燕[1] 紫绍贵 李宝香 石丽媛[1] ZHANG Haipeng;PENG Haiyan;ZI Shaogui;LI Baoxiang;SHI Liyuan(Yunnan Provincial Key Laboratory for Zoonosis Control and Prevention,Yunnan Institute for Endemic Disease Control and Prevention,Dali,Yunnan 671000,China)

机构地区：[1]云南省地方病防治所,云南省自然疫源性疾病防控技术重点实验室,云南大理671000

出　　处：《中国地方病防治》2024年第6期451-453,共3页Chinese Journal of Control of Endemic Diseases

基　　金：云南省中青年学术和技术带头人(202405AC350058)。

摘　　要：目的探究某种以十二烷基二甲基苄基氯化铵为主要成分的复方消毒剂对鼠疫菌以及炭疽芽孢杆菌的消毒效果,为其投入实际应用提供依据。方法参考《消毒技术规范》(2002版)消毒效果评价方法,采用悬液定量消毒法,选用鼠疫菌EV76及炭疽芽孢杆菌A16R作为指示菌进行中和剂鉴定及消毒效果评价试验,对该消毒剂的消毒性能进行评估。结果中和剂鉴定试验重复3次,鼠疫菌EV76及炭疽芽孢杆菌A16R中和剂鉴定均合格;消毒液原液作用2 min后,对鼠疫菌EV76与炭疽芽孢杆菌A16R的杀灭对数值均>5.00,消毒效果合格;消毒剂原液稀释10倍对鼠疫菌EV76的杀灭对数值>5.00,消毒效果合格,对炭疽芽孢杆菌A16R的杀灭对数值均<5.00,消毒效果不合格。结论该复方消毒剂原液能够有效杀灭鼠疫菌EV76与炭疽芽胞杆菌A16R,且当该消毒剂稀释10倍后,仍能有效杀灭鼠疫菌EV76。Objective To explore the disinfection effect of a compound disinfectant with dodecyl dimethyl benzyl ammonium chloride as the main component on Yersinia pestis and Bacillus anthracis,and to provide the basis for its practical application.Methods With reference to the disinfection effect evaluation method of Disinfection Technical Specification(2002)Version,the suspension quantitative disinfection method was adopted,and Yersinia pestis EV76 and Bacillus anthracis A16R were selected as the indicator bacteria to carry out the evaluation test of neutralization agent identification and disinfection effect evaluation,and the disinfection performance of this disinfectant was assessed.Results The neutralizing agent identification test was repeated 3 times,Yersinia pestis EV76 and Bacillus anthracis A16R were qualified;After 2 min of action of the original solution of the disinfectant,the killing logarithmic value of Yersinia pestis EV76 and Bacillus anthracis A16R was greater than 5.00,and the disinfecting effect was qualified;The killing logarithmic value of the disinfectant stock solution diluted 10 times to Yersinia pestis EV76 was more than 5.00,and the disinfecting effect was qualified.For Bacillus anthracis A16R,the killing logarithm value was less than 5.00,and the disinfecting effect was unqualified.Conclusions The compound disinfectant of the original solution is able to effectively kill the Yersinia pestis EV76 and Bacillus anthracis A16R,and when the disinfectant is diluted 10 times,it is still able to effectively kill the Yersinia pestis EV76.

关 键 词：消毒剂 鼠疫菌 炭疽芽孢杆菌 消毒效果评价 

分 类 号：R516.8[医药卫生—内科学]