社区2型糖尿病患者慢性并发症患病现状及其影响因素分析  

Status quo and influencing factors of chronic complications in type 2 diabetes mellitus patients in community

作　　者：时巧梅 蒋萌 王猛猛 解晔 李秋梅 赵培 胡乃元 王琦玮 陈雪筠 SHI Qiaomei;JIANG Meng;WANG Mengmeng;XIE Ye;LI Qiumei;ZHAO Pei;HU Naiyuan;WANG Qiwei;CHEN Xueyun(Yangzhou City Center for Disease Control and Prevention,Yangzhou 225000,China;Yangzhou City Guangling District Center for Disease Control and Prevention,Yangzhou 225002,China)

机构地区：[1]扬州市疾病预防控制中心,江苏扬州225000 [2]扬州广陵区疾病预防控制中心,江苏扬州225002

出　　处：《东南大学学报（医学版）》2024年第6期837-844,共8页Journal of Southeast University(Medical Science Edition)

基　　金：扬州市卫健委科研专项资金资助项目(2023-4-23)。

摘　　要：目的:了解我市2型糖尿病患者慢性并发症患病情况,探究其可能的影响因素,为我市制定糖尿病管理相关政策提供依据。方法:2023年10月通过分层抽样的方法从国家基本公共卫生服务系统中抽取我市600名在管的糖尿病患者,采用问卷+体格测量+生化检测相结合的方式收集信息,描述糖尿病患者慢性并发症患病现状及其影响因素分析。结果:共562例糖尿病患者纳入研究,平均年龄(67.53±8.35)岁,慢性并发症的患病率为97.5%。多因素Logistic回归分析结果显示:合并高血压、血脂异常是糖尿病足(OR=2.61,95%CI:2.03~3.36)、糖尿病肾病(OR=2.05,95%CI:1.62~2.60)、周围神经病变(OR=2.43,95%CI:1.89~3.12)、糖尿病视网膜病变(OR=1.85,95%CI:1.47~2.33)、脑血管疾病(OR=4.10,95%CI:2.93~5.75)、心血管疾病(OR=4.46,95%CI:3.14~6.34)等2型糖尿病慢性并发症的危险因素;此外,高体质量指数(BMI)是糖尿病肾病(OR=1.10,95%CI:1.01~1.19)、心血管疾病(OR=1.12,95%CI:1.03~1.23)、脑血管疾病(OR=1.11,95%CI:1.00~1.22)等慢性并发症的危险因素;收缩压(SBP)是脑血管疾病(OR=1.03,95%CI:1.00~1.06)的危险因素;没有午睡习惯是糖尿病视网膜病变(OR=1.88,95%CI:1.09~3.24)的危险因素。结论:重视糖尿病患者慢性并发症,对于没有午睡习惯、合并肥胖以及同时患有高血压和(或)血脂异常等患者,应及时纠正不良生活习惯,定期筛查,提高糖尿病患者的生存质量。Objective:To understand the chronic complications of type 2 diabetes mellitus patients in our city,explore its possible influencing factors,and provide a basis for the development and management of diabetes-related policies in our city.Methods:In October 2023,600 patients with diabetes in our city were selected from the National Basic Public Health System through stratified sampling,and the information was collected by means of questionnaire+physical measurement+biochemical detection to describe the status quo of chronic complications of diabetes patients and the influencing factors were analyzed.Results:A total of 562 patients with diabetes were included in the study,with a mean age of(67.53±8.35)years,and the prevalence of chronic complications was 97.5%.The results of multivariate Logistic regression analysis showed:the combination of hypertension and dyslipidemia was a risk factor for chronic complications of type 2 diabetes,such as diabetic foot(OR=2.61,95%CI:2.03-3.36),diabetic nephropathy(OR=2.05,95%CI:1.62-2.60),peripheral neuropathy(OR=2.43,95%CI:1.89-3.12),diabetic retinopathy(OR=1.85,95%CI:1.47-2.33),cerebrovascular diseases(OR=4.10,95%CI:2.93-5.75),and cardiovascular diseases(OR=4.46,95%CI:3.14-6.34).In addition,high body mass index(BMI)was the risk factor for chronic complications such as diabetic nephropathy(OR=1.10,95%CI:1.01-1.19),cardiovascular disease(OR=1.12,95%CI:1.03-1.23),and cerebrovascular disease(OR=1.11,95%CI:1.00-1.22).Systolic pressure(SBP)was a risk factor for cerebrovascular disease(OR=1.03,95%CI:1.00-1.06).Non-habitual nap was a risk factor for diabetic retinopathy(OR=1.88,95%CI:1.09-3.24).Conclusion:Attention should be paid to the chronic complications of diabetic patients.For patients with non-habitual nap,combined obesity,and patients with hypertension and(or)dyslipidemia,bad living habits should be corrected in time and regular screening should be conducted to improve the quality of life of diabetic patients.

关 键 词：2型糖尿病 慢性并发症 患病现状 影响因素 

分 类 号：R587.1[医药卫生—内分泌] R587.2[医药卫生—内科学]