多模态磁共振成像技术在癫痫丘脑中的研究进展  

Research progress of magnetic resonance imaging in epileptic thalamus

作　　者：夏淑媛 王文[1] 任庆发 刘宇威 巩贺 刘苗苗 李祥林[1] XIA Shuyuan;WANG Wen;REN Qingfa;LIU Yuwei;GONG He;LIU Miaomiao;LI Xianglin(Department of Radiology,Binzhou Medical University Hospital,Binzhou 256600,China;School of Medical Imaging,Binzhou Medical University,Yantai 264003,China)

机构地区：[1]滨州医学院附属医院放射科,滨州256600 [2]滨州医学院医学影像学院,烟台264003

出　　处：《磁共振成像》2024年第12期165-170,共6页Chinese Journal of Magnetic Resonance Imaging

基　　金：国家自然科学基金项目(编号:62176181);山东省重点研发计划项目(编号:2018YFJH0501)。

摘　　要：癫痫是一种由脑神经元异常放电引起的慢性神经系统疾病,主要临床症状包括抽搐、意识丧失、肌阵挛、肌张力降低及肌收缩持续时间延长等。丘脑为癫痫神经网络中的关键枢纽,参与癫痫的发作、传播等重要阶段。MRI技术可探索脑结构、功能活动与神经代谢物的改变,为神经系统疾病研究提供了一种无创的重要工具,对研究癫痫患者的神经改变具有重要意义。因此,本文就多模态MRI技术在癫痫患者丘脑中的研究现状予以综述,旨在深入了解癫痫的病理机制及发展诊疗策略。Epilepsy is a chronic nervous system disease caused by abnormal discharge of brain neurons.The main clinical symptoms include convulsions,loss of consciousness,myoclonus,decreased muscle tone and prolonged muscle contraction duration.The thalamus is a key hub in the epilepsy neural network,which is involved in the onset,transmission and other important stages of epilepsy.MRI technology can explore the changes of brain structure,functional activity and neural metabolites,which provides an important non-invasive tool for the study of nervous system diseases,and is of great significance for the study of neurological changes in patients with epilepsy.Therefore,this paper reviews the research status of multimodal MRI techniques in the thalamus of epileptic patients,aiming to further understand the pathological mechanism of epilepsy and develop diagnosis and treatment strategies.

关 键 词：癫痫 丘脑 磁共振结构成像 磁共振波谱 磁共振成像 血氧水平依赖 

分 类 号：R445.2[医药卫生—影像医学与核医学] R742.1[医药卫生—诊断学]