骶骨原发性肿瘤的^(18)F-FDG PET/CT表现  

The^(18)F-FDG PET/CT Manifestations of Primary Sacrum Tumor

作　　者：陈紫薇 张连娜 冯瑾 杨芳 CHEN Ziwei;ZHANG Lianna;FENG Jin;YANG Fang(Department of Nuclear Medicine,Beijing Jishuitan Hospital,Capital Medical University,Beijing100035,China)

机构地区：[1]首都医科大学附属北京积水潭医院核医学科,北京市100035

出　　处：《中国医学计算机成像杂志》2024年第6期744-748,共5页Chinese Computed Medical Imaging

摘　　要：目的:分析骶骨原发性肿瘤的^(18)F-氟代脱氧葡萄糖(^(18)F-FDG)PET/CT表现。方法:回顾性分析经病理诊断确诊的31例骶骨原发性肿瘤的PET/CT资料,观察骶骨病变的位置、影像学特征、^(18)F-FDG摄取程度以及其他部位受累的情况,并对患者的年龄、肿瘤大小及最大标准化摄取值(SUVmax)进行统计学分析。结果:本组骶骨原发性肿瘤中以尤文肉瘤(19.4%)、脊索瘤(16.1%)、骨巨细胞瘤(16.1%)、未分化肉瘤(12.9%)、软骨肉瘤(9.7%)为主,尤文肉瘤、脊索瘤、骨巨细胞瘤、未分化肉瘤患者的中位年龄有统计学差异(H=14.774,P=0.002)。骶骨肿瘤的基线SUVmax平均值为11.97±8.63,尤文肉瘤、脊索瘤、骨巨细胞瘤、未分化肉瘤、软骨肉瘤的SUVmax有统计学差异(F=15.950,P<0.001)。低级别与高级别恶性肿瘤的SUVmax有统计学差异(t=-4.505,P=0.001)。结论:不同类型的骶骨原发性肿瘤在年龄及代谢活性中有一定差异,PET/CT可以帮助肿瘤的诊断及分期。Purpose:To analyze the^(18)F-fluorode-oxyglucose(^(18)F-FDG)PET/CT manifestations of primary sacral tumors.Methods:Thirty-one patients who underwent PET/CT examination and pathologically diagnosed with primary sacral tumors were retrospectively analyzed.The location,imaging features,^(18)F-FDG uptake and other lesions of sacrum were observed,and the patient's age,tumor size and maximum standardized uptake value(SUVmax)were statistically analyzed.Results:Among primary sacral tumors in this group,6 cases(19.4%)were Ewing sarcoma,5 cases(16.1%)were chordoma and giant cell tumor of bone,4 cases(12.9%)were undifferentiated sarcoma,and 3 cases(9.7%)were chondrosarcoma.There was a statistically significant difference in median age among patients with different diseases,including Ewing sarcoma,chordoma,giant cell tumor of bone,and undifferentiated sarcoma(H=14.774,P=0.002).The average baseline SUVmax of sacral tumors was 11.97±8.63,and there was a statistical difference among Ewing sarcoma,chordoma,giant cell tumor of bone,undifferentiated sarcoma and chondrosarcoma(F=15.950,P<0.001).And there was a statistical difference in SUVmax between lowgrade and high-grade malignant tumors(t=-4.505,P=0.001).Conclusion:Primary sacral tumors are different in age and metabolic activity.PET/CT have great value of the diagnosis and staging in sacral tumors.

关 键 词：骶骨 骨与软组织肿瘤 正电子发射计算机体层成像 ^(18)F-氟代脱氧葡萄糖 

分 类 号：R445[医药卫生—影像医学与核医学] R681[医药卫生—诊断学]