冠状动脉CT血管造影判断冠心病病变情况的价值分析  

Analysis of the Value of Coronary CT Angiography in Determining Lesions in Patients with Coronary Artery Disease

作　　者：吴丹 Wu Dan(Department of Medical Imaging,The Second Affiliated Hospital of Nanyang Medical College,Nanyang 473000,Henan Province,China)

机构地区：[1]南阳医学高等专科学校第二附属医院医学影像科,河南南阳473000

出　　处：《罕少疾病杂志》2025年第1期74-76,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的 探究冠状动脉计算机断层扫描(CT)血管造影判断冠心病患者病变情况的应用效果。方法 回顾性选取本院2022年4月至2023年4月收治的97例冠心病患者作为研究样本,依据入选者斑块进展情况分组,将入选者分为冠心病进展期组(n=58)及冠心病稳定期组(n=39),所有入选者均接受冠状动脉CT血管造影检查。对比两组重构指数(RI)、斑块负荷、高危斑块(HRP)占比、斑块体积等冠状动脉CT血管造影检查参数,分析上述参数与冠心病斑块进展程度之间的相关性,并绘制受试者工作特征(ROC)曲线,计算曲线下面积(AUC)、灵敏度、约登指数、最佳阈值。结果 冠心病进展期组RI及斑块负荷水平、HRP占比、斑块体积均高于冠心病稳定期组(P<0.05)。上述参数与冠心病斑块进展程度之间均为正相关关系(r=0.758、0.620、0.611、0.616,P<0.05),且RI、斑块负荷、HRP占比、斑块体积的AUC值分别为0.958、0.870、0.811、0.873,AUC值均>0.6。结论 冠状动脉CT血管造影检查参数(RI、斑块负荷、HRP占比、斑块体积)与冠心病斑块进展程度呈正性相关,上述参数对冠心病斑块进展程度的诊断价值优良。Objective To investigate the application effect of coronary artery computed tomography(CT)angiography in determining lesions in patients with coronary heart disease.Methods Retrospectively selected 97 cases of coronary artery disease patients admitted in our hospital from April 2022 to April 2023 as study samples,grouped according to the plaque progression of the enrollees,and divided the enrollees into coronary artery disease progression group(n=58)and coronary artery disease stabilization group(n=39),and all of the enrollees were subjected to coronary artery CT angiography examination.Coronary CT angiography parameters such as remodeling index(RI),plaque load,percentage of high-risk plaque(HRP),and plaque volume were compared between the two groups to analyze the correlation between the above parameters and the degree of progression of coronary artery disease plaques,and to draw the subjects'workup characteristic(ROC)curves,and to calculate the area under the curve(AUC),the sensitivity,the Jordon's index,and the optimal threshold value.Results The RI and plaque load levels,HRP percentage,and plaque volume were higher in the coronary heart disease progression group than in the coronary heart disease stabilization group(P<0.05).There was a positive correlation between all of the above parameters and the degree of coronary plaque progression(r=0.758,0.620,0.611,0.616,P<0.05),and the AUC values of RI,plaque load,HRP percentage,and plaque volume were 0.958,0.870,0.811,0.873,respectively,with an AUC value of>0.6.Conclusion Coronary CT angiographic Angiography parameters(RI,plaque load,HRP percentage,plaque volume)are positively correlated with the degree of coronary plaque progression,and the above parameters have excellent diagnostic value for the degree of coronary plaque progression.

关 键 词：冠状动脉 计算机断层扫描 血管造影 冠心病 

分 类 号：R541.4[医药卫生—心血管疾病]