卡前列素氨丁三醇联合改良B-lynch缝合术用于前置胎盘剖宫产出血效果及妊娠结局  

Effectiveness of Carboprost Tromethamine Combined with Modified B-lynch Suture for Cesarean Haemorrhage with Placenta Praevia and Pregnancy Outcome

作　　者：叶晶晶 刘慧云 YE Jing-jing;LIU Hui-yun(Department of Obstetrics(Area3),Women and Infants Hospital of Zhengzhou,Zhengzhou 450000,Henan Province,China)

机构地区：[1]郑州市妇幼保健院产科三区,河南郑州450000

出　　处：《罕少疾病杂志》2025年第1期105-107,共3页Journal of Rare and Uncommon Diseases

基　　金：快速反应团队协同预警评分系统治疗产科重症患者的效果研究(LHGJ20200744)。

摘　　要：目的 探究卡前列素氨丁三醇联合改良B-lynch缝合术治疗前置胎盘剖宫产出血效果。方法 选择2021年3月至2023年3月在我院剖宫产前置胎盘患者198例,应用随机数表法将其分为对照组(改良B-lynch缝合术)及观察组(联合卡前列素氨丁三醇)各99例,对比两组临床疗效、止血效果、凝血指标[纤维蛋白原(FIB)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)]、妊娠结局。结果 对照组治疗有效率低于观察组,差异有统计学意义(P<0.05)。观察组术中出血量、术后2h和24h出血量、输血量少于对照组,差异有统计学意义(P<0.05)。治疗前,两组PT、APTT、FIB差异无统计学意义(P>0.05);治疗后,两组FIB升高、PT、APTT降低,对照组FIB低于观察组,PT、APTT高于观察组,差异有统计学意义(P<0.05)。对照组子宫切除、产褥期感染、术后腹痛发生率高于观察组,差异有统计学意义(P<0.05)。结论 前置胎盘剖宫产出血患者接受卡前列素氨丁三醇联合改良B-lynch缝合术止血,疗效显著,能够减轻应激反应,改善凝血功能,改善妊娠结局、降低并发症发生率。Objective To investigate the effect of carboprost tromethamine combined with modified B-lynch suture in the treatment of cesarean haemorrhage with placenta praevia.Methods 198 cases of patients with placenta praevia delivered by cesarean section in our hospital were selected from March 2021 to March 2023,and were divided into 99 cases each in the control group(modified B-lynch suture)and the observation group(combined with carboprost tromethamine)by applying the method of random number table,and the two groups were compared in terms of clinical efficacy,haemostatic effect,coagulation indexes[fibrinogen(FIB),plasminogen time(PT),activated partial thromboplastin time(APTT)],and the effectiveness of the treatment.partial thromboplastin time(APTT)],and pregnancy outcome.Results The treatment efficiency of the control group was lower than that of the observation group,and the difference was statistically significant(P<0.05).Intraoperative bleeding,postoperative bleeding at 2h and 24h,and blood transfusion were less in the observation group than in the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference in PT,APTT and FIB between the two groups(P>0.05);after treatment,FIB increased and PT and APTT decreased in the two groups,with FIB in the control group lower than that of the observation group,and PT and APTT higher than that of the observation group,with statistically significant differences(P<0.05).The incidence of hysterectomy,puerperal infection and postoperative abdominal pain in the control group was higher than that in the observation group,and the difference was statistically significant(P<0.05).Conclusion Patients with placenta praevia undergoing cesarean section for haemorrhage received carboprost tromethamine combined with modified B-lynch suture for haemostasis with remarkable efficacy,which was able to alleviate the stress reaction,improve coagulation function,improve pregnancy outcome,and reduce the incidence of complic

关 键 词：卡前列素氨丁三醇 改良B-ynch缝合术 前置胎盘剖宫产出血 妊娠结局 

分 类 号：R714.461[医药卫生—妇产科学]