银甲丸加减联合阿奇霉素治疗生殖道支原体感染(湿热瘀阻型)的临床观察  

Clinical Observation of Yinjia Pill Combined with Azithromycin in Treating Genital Tract Mycoplasma Infection(Damp-heat Stasis Type)

作　　者：陈乐 王淑敏 李紫艳 乔江[2] 陈圆 CHEN Le;WANG Shu-min;LI Zi-yan;QIAO Jiang;CHEN Yuan(Zhumadian Hospital of Traditional Chinese Medicine,Zhumadian 463000,Henan Province,China;The First Affiliated Hospital of Hunan University of Chinese Medicine,Changsha 410000,Hunan Province,China)

机构地区：[1]驻马店市中医院,河南驻马店463000 [2]湖南中医药大学第一附属医院,湖南长沙410000

出　　处：《罕少疾病杂志》2025年第1期110-112,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的 对中药银甲丸(针对湿热瘀阻型)联合阿奇霉素治疗女性生殖道支原体感染的临床效果进行总结和分析。方法 选择2019年9月至2021年9月期间我科住院部收治的40例生殖道支原体感染女性患者(湿热瘀阻型)为观察组研究对象,联合给予中药银甲丸加减、阿奇霉素治疗。另将同期收住的40例患者纳入对照组,单纯应用阿奇霉素治疗。对两组患者支原体转阴率、不良反应率、中医证候积分、临床疗效进行观察对比。结果 (1)观察组UU转阴率92.5%高于对照组80.00%,存在差异(P<0.05);观察组不良反应率为10.00%、对照组为8.00%,两组之间不存在差异(P>0.05)。(2)两组治疗前患者的各项中医证候积分比较,不存在差异(P>0.05);两组治疗后患者的各项中医证候积分与治疗前比较,均降低,存在差异(P<0.05);治疗后,观察组中医证候改善显著,积分远低于对照组,存在显著差异(P<0.01)。(3)观察组40例患者的临床治疗总有效率为85%,高于对照组75%,存在差异(P<0.05)。结论 阿奇霉素联合中药银甲丸(针对症状加减)治疗女性生殖道支原体感染,效果突出,两者协同作用显著,为该病的治疗提供了新的有效方案,值得在临床实践中推广与应用。Objective To summarize and analyze the clinical effect of Yinjia Pill(adjusted according to symptoms)combined with azithromycin on female genital tract mycoplasma infection(damp-heat stasis type).Methods From September 2019 to September 2021,40 female patients with genital tract mycoplasma infection(damp-heat stasis type)admitted to the inpatient department of our department were selected as the observation group,and were treated with Yinjia Pill and Azithromycin.Another 40 patients admitted in the same period were included in the control group and treated with azithromycin alone.The mycoplasma negative conversion rate,adverse reaction rate,TCM syndrome score and clinical curative effect of the two groups were observed and compared.Results ①The negative conversion rate of UU in observation group was 92.5%higher than that in control group(80.00%,P<0.05);the incidence of adverse effects was 10%for the observation cohort and 8%for the control,showing no significant disparity between them(P>0.05).②Prior to therapy,both groups exhibited comparable TCM syndrome scores(P>0.05).After treatment,the scores of TCM syndromes of the patients in the two groups decreased compared with those before treatment,and there was a difference(P<0.05).Post-treatment,the observation group showed notably reduced TCM syndrome scores compared to the control group(P<0.01).③The total effective rate of clinical treatment of 40 patients in the observation group was 85%,which was higher than 75%in the control group(P<0.05).Conclusion Azithromycin combined with Chinese medicine Yinjia Pill(adjusted according to symptoms)has shown outstanding effects in female genital tract mycoplasma infection.The synergistic effects of the two treatments are significant,providing a new effective treatment option for this disease.It is worth promoting and applying in clinical practice.

关 键 词：银甲丸加减 阿奇霉素 生殖道支原体 湿热瘀阻型 

分 类 号：R711.33[医药卫生—妇产科学]