陕西地区过敏性紫癜性肾炎患者中医证候分布规律研究  

Study on the TCM Syndrome Distribution Law of Patients with Henoch-Schonlein Purpura Nephritis in Shaanxi Area

作　　者：杨文君 董盛 赵若岚 雷根平 王婷 YANG Wenjun;DONG Sheng;ZHAO Ruolan;LEI Genping;WANG Ting(Shaanxi University of Chinese Medicine,Xianyang 712046,China;Hospital of Shaanxi University of Chinese Medicine,Xianyang 712000,China)

机构地区：[1]陕西中医药大学,陕西咸阳712046 [2]陕西中医药大学附属医院,陕西咸阳712000

出　　处：《中国中医药信息杂志》2025年第1期146-150,共5页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：陕西省中医药管理局中医药科研课题(SZY-KJCYC-2023-015);咸阳市科学技术重点研发计划项目(2020k02-92);咸阳市科技创新团队项目(2019年)。

摘　　要：目的探讨陕西地区过敏性紫癜性肾炎的证候特点,为中医临床辨证论治提供参考。方法回顾性收集2020年8月-2022年8月陕西中医药大学附属医院、榆林市中医院等陕西地区5所医院门诊或住院治疗的过敏性紫癜性肾炎患者四诊资料,通过频数统计、聚类分析、主成分分析和复杂网络分析,归纳陕西地区过敏性紫癜性肾炎患者中医证候分布规律。结果共纳入143例患者四诊资料,涉及症状64种,聚类分析后得到3组证候,并对各组证候进行主成分分析。运用复杂网络分析,结合聚类分析和主成分分析的结果,形成各组主症、兼症分类群,最终判定其主要证候分类:以气阴两虚为主占47.55%,以脾虚湿盛为主占34.97%,以风热袭表为主占17.48%。结论陕西地区过敏性紫癜性肾炎证候主要分为气阴两虚、脾虚湿盛、风热袭表,其中气阴两虚类型最为常见。Objective To explore the syndrome characteristics of Henoch-Schonlein purpura nephritis in Shaanxi area;To provide reference for TCM clinical syndrome differentiation and treatment.Methods Clinical data on patients diagnosed with Henoch-Schonlein purpura nephritis who received outpatient or inpatient treatment at five hospitals in Shanxi area including Hospital of Shaanxi University of Chinese Medicine and Yulin Traditional Chinese Medicine Hospital etc from August 2020 to August 2022 were under retrospective collection.TCM syndrome distribution law in patients with Henoch-Schonlein purpura nephritis in Shaanxi area was concluded through frequency statistics,clustering analysis,principal component analysis,and complex network analysis.Results Totally 143 patients were included,involving 64 symptoms.3 groups of syndromes were obtained after clustering analysis,and principal component analysis was performed for each group of syndromes.Using complex network analysis and combining the results of clustering analysis and principal component analysis,classification groups for each group of main symptoms and comorbidities were formed,and their main syndrome classification was determined:qi-yin deficiency syndrome,accounting for 47.55%;spleen deficiency and dampness,accounting for 34.97%;wind-heat attacking the exterior,accounting for 17.48%.Conclusion The syndromes of Henoch-Schonlein purpura nephritis in Shaanxi area are mainly divided into three types:qi-yin deficiency,spleen deficiency and dampness and wind-heat attacking the exterior.Among them,qi-yin deficiency is the most common.

关 键 词：过敏性紫癜性肾炎 中医证候 聚类分析 主成分分析 复杂网络分析 

分 类 号：R277.51[医药卫生—中医学]