二茂铁类环肽的合成与分子识别研究  

Synthesis of a Family of Ferrocene-bearing Cyclo-pseudo-peptides by Liquid Method and Molecular Recognition

作　　者：韩前伟[1] 朱晓晴[1] 胡旭波[1] 程津培[1] 

机构地区：[1]南开大学化学系,元素有机化学国家重点实验室,天津300071

出　　处：《高等学校化学学报》2002年第11期2076-2079,共4页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金 (批准号 :2 0 0 72 0 2 0和 2 9832 0 40 );国家自然科学杰出青年基金 (批准号 :2 0 12 5 0 6 )资助

摘　　要：设计并合成了两个系列含二茂铁单元的 1 + 1型和 2 + 2型类环肽 ,用循环伏安法研究了 1 + 1型二茂铁类环肽与含氧负离子和卤素负离子的包合作用 .结果表明 ,类环肽能很好地识别这些常见的负离子 .1 H NMR研究发现 ,类环肽对负离子的识别作用主要是通过类环肽酰胺键中氢与客体负离子形成分子间氢键实现的 .Two series of new ferrocene-bearing cyclo-pseudo-peptides, including three 1+1 type and three 2+2 type compounds, were designed and synthesized by liquid method. The interactions of the 1+1 type cyclo-pseudo-peptides as the host compounds with some anions were investigated by cyclic voltammetry(CV) and 1H NMR methods. The results show that the 1+1 type hosts can selectively interact with the guest anions by intermolecular hydrogen bond. A reasonable interaction model of the 1+1 type cyclo-pseudo-peptides with anions was proposed.

关 键 词：二茂铁类环肽 合成 分子识别 超分子化学 

分 类 号：O629.72[理学—有机化学] O641[理学—化学]