经皮椎体成形术的实验研究及临床应用  

Percutaneous polymethylmethacrylate vertebroplasty:methods and clinical application

作　　者：樊仕才[1,2] 江振华[1,2] 朱青安 万黎 赵卫东[1,2] 钟世镇 

机构地区：[1]广东省创伤救治科研中心,深圳市沙井人民医院骨科,广东深圳518104 [2]第一军医大学解放军医用生物力学实验室,广东广州510515

出　　处：《中国临床解剖学杂志》2002年第6期481-483,共3页Chinese Journal of Clinical Anatomy

基　　金：广东省自然科学基金 ( 99B0 6 70 3G)

摘　　要：目的 :完善经皮椎体成形术的方法并对其临床疗效进行评价。方法 :5具新鲜胸腰段脊柱 (T9～L5)标本随机选取 1 0个椎体节段行椎体成形术 ,观察PMMA在椎体内分布并进行椎体压缩试验。临床选择 4例骨质疏松腰椎压缩性骨折患者行经皮椎体成形术 ,观察其临床效果。结果 :1 0个椎体节段均穿刺顺利 ;PMMA骨水泥在椎体内沿骨小梁分布至整个椎体 ,有 1例出现椎体后静脉窦渗漏 ;椎体成形术后抗压强度由 (2 1 97± 355)N增加至 (4861 +1 1 0 9)N ;临床治疗 4例患者疗效好 ,未出现椎体外漏导致的并发症。结论 :在C臂X线机透视引导下经皮椎体成形术安全、可靠 ;Objective:To describe the technique and method for percutaneous polymethylmethacrylate(PMMA)vertebroplasty and to evaluate the biomechanical stability of osteoporosis vertebroplasty. Methods:Five cadaveric thoracolumbar spines were harvested and 10 vertebrae were selected randomly.Under 'C' X ray control,percutaneous puncture via a transpedicular approach followed by injection of PMMA was done and then the capacity and thickness of PMMA distribution were recorded.The vertebral bodies of ten cases of osteoporosis depress fracture were compressed after vertebroplasty,and the strength and stiffness were measured.Results:The procedure was technically successful in all specimens,with an average injection amount of 8ml PMMA per vertebral body.PMMA was distributed all over the vertebrae.The strength and stiffness of osteoporosis vertebral bodies had increased from 2197±355N(stiffness,499+86N/mm) to 4861±1109N (stiffness,1128±175N/mm).Conclusion: Percutaneous PMMA vertebroplasty is a valuable clinical therapeutic method in spine osteoporosis depresses fracture.

关 键 词：经皮椎体成形术 聚甲基丙烯酸甲酯 骨质疏松 椎体压缩性骨折 

分 类 号：R681[医药卫生—骨科学]