^(99)Tc^m-ECDSPECT显像定位致灶的价值  

The evaluation of SPECT in the localization of epileptic foci

作　　者：刘灿虎[1] 芮东红[2] 李冰[1] 张金伟[1] 张丽君[1] 金子焕 金道云[1] 

机构地区：[1]哈尔滨医科大学附属第二医院伽玛刀治疗中心,150086 [2]哈尔滨医科大学附属第二医院核医学科,150086

出　　处：《中华核医学杂志》2002年第5期279-280,T001,共3页Chinese Journal of Nuclear Medicine

基　　金：黑龙江省卫生厅科研基金资助项目 (970 4 5)

摘　　要：目的　探讨99Tcm 双半胱乙酯 (ECD)SPECT显像对原发性癫致灶定位的价值。方法　经临床和头皮脑电图 (EEG)诊断为癫的 3 4例患者行SPECT发作间期及发作期局部脑血流(rCBF)显像 ,以确定致灶。结果　 2 2例患者发作间期rCBF显像出现rCBF灌注减低 ,2 8例发作期显示血流灌注增加 ,两期吻合的部位确定为致灶 ,据此行伽玛刀治疗。结论　SPECT对致灶定位有很大价值。Objective To explore the value of SPECT in the localization of epileptic foci. Methods To determine epileptic foci, 34 epilepsy patients who were diagnosed by clinical history and EEG underwent ictal and interictal regional cerebral blood flow (rCBF) imaging with SPECT. Results Twenty-two of 34 cases showed decreased brain blood flow perfusion on the interictal rCBF images, 28 of those showed increased brain blood flow perfusion on the ictal rCBF images. The patients whose epileptic foci had been localized by SPECT were treated with γ knife. Conclusion SPECT is of great value in the localization of epileptic foci.

关 键 词：^99TC^M-ECD SPECT显像 癫痫 ECD 病灶定位 

分 类 号：R817[医药卫生—影像医学与核医学]