窒息新生儿血小板参数的动态变化及其意义  

THE DYNAMIC CHANGES OF PLATELET PARAMETES IN ASPHCITIC NEONATE AND THEIR VALUES.

作　　者：徐丽云 徐益群[2] 徐淑娟 

机构地区：[1]山东省临沂医专儿科教研室,27600 [2]山东临沂市人民医院儿科 [3]山东临沂市计划生育技术指导所

出　　处：《中国小儿血液》2002年第5期207-209,共3页China Child Blood

摘　　要：为了解窒息新生儿血小板数 (PLT)、血小板平均容体 (MPV)及血小板分布宽度 (PDW)的变化及其临床意义。方法　采用全自动血细胞分析仪测定 83例窒息新生儿及 80例正常新生儿的PLT、MPV及PDW。结果　新生儿窒息后 ,急性期PLT较正常对照组显著降低 (P <0 0 1) ,MPV和PDW则较对照组明显增高 (P <0 0 5 ) ,窒息组恢复期PLT、MPV和PDW与对照组比较 ,其差异无统计学意义 (P >0 0 5 )。且随着窒息程度加重 ,PLT愈下降 (中度组与轻度组比较P <0 0 0 1) ,而MPV、PDW则愈增高 (中度组与轻度组比较P <0 0 5 ,重度组与轻度组比较P <0 0 1)。结论　血小板参数 (PLT、MPV和PDW)可做为项判断新生儿窒息后病情严重程度并监测病情变化的指标。Objective To explore the changes of PLT, mean plaelet volume MPV and platelet distribution width PDW in asphyxiant neonates and their clinical values. Methods Automatic blood cell analyzer was used to detect the PLT, MPV and PDW in 83 cases of asphyxia and 80 normal cases. Results The PLT of asphyxiant neonates in their acute stage decreased obviously than in the contrast group ( P<0.01 ). MPV and PDW increased more markedly in the treatment group than in the contrast group ( P<0.05 ). PLT, MPV and PDW in patients, restoration stage showed no significant difference betweenthe two groups ( P>0.05 ). As asphyxia grew more serious, PLT decreased (Ogvious difference existing between the group of moderate cases and the group of slight cases), while MPV and PDW increased (Obvious differences existing between the groups of moderate cases and slight ones, P<0.05 ; and also between the moderate cases and severe cases, P<0.05 ). Conclusion PLT, MPV and PDW can be used as parameters to monitor patients, conditions and to judge the degreeof asphyxia

关 键 词：新生儿窒息 血小板参数 动态变化 临床意义 

分 类 号：R722.12[医药卫生—儿科]