手性有机磷化合物液相色谱拆分的研究进展  

Advances in the Chiral Resolution of Organophosphorus Compounds by Liquid Chromatography

作　　者：周爱玲[1] 吕宪禹[2] 黄君珉[1] 王新省[1] 高如瑜[1] 

机构地区：[1]南开大学化学学院,天津300071 [2]南开大学生命科学学院,天津300071

出　　处：《色谱》2002年第6期502-507,共6页Chinese Journal of Chromatography

摘　　要：综述了近年来手性有机磷化合物液相色谱拆分的研究进展。对间接拆分和直接拆分法,特别是各类手性固定相法在拆分有机磷化合物中的应用作了介绍,探讨了相应的拆分机理。引用文献85篇。The developments in the chiral resolution of organophosphorus compounds by liquid chromatography in recent years are reviewed. Two different approaches of separation: indirect resolution (chiral derivatization reagent method) and direct resolution (chiral mobile phase additive and chiral stationary phase), focusing on several chiral stationary phasesPirkle type,cyclodextrin,cellulose,ligand exchange and other chiral stationary phases are presented. The possible mechanism of chiral recognition is discussed. Eightyfive references are involved.

关 键 词：液相色谱 手性固定相 有机磷化合物 手性拆分 

分 类 号：O627.51[理学—有机化学] O658[理学—化学]