4-(7’-阿朴-β-胡萝卜素-7’基)酚的合成研究  

The Synthesis of 4-(7'-apo-β-caroten-7'-yl)Phenol

作　　者：徐平俊 卓启疆 李坤福[1] 

机构地区：[1]成都科技大学高分子研究所

出　　处：《成都科技大学学报》1992年第4期13-18,共6页

基　　金：八六三计划资助项目

摘　　要：通过Wittig反应由β-阿朴-8’-胡萝卜醛合成了4-（7’-阿朴-β-胡萝卜）苯甲醚,采用BBr₃作去甲基化试剂,制备了4-（7’-阿朴-β-胡萝卜-7’基）苯酚。采用IR,MS,¹HNMR鉴定了产物的结构。实验发现对硝基苯基亚甲基化三苯基膦与β-阿朴-8’-胡萝卜醛不能进行Wittig反应。4-(7'-apo-β-caroten-7'-yl)phenyl methyl ether was synthesised using wittig reaction of β-apo-8'-carotenal with methoxyphenyl methylene triphenylphosphorane. 4-(7'-apo-β-caroten-7'-yl)phenol was prepared by cleavage of ether with BBr_3. Products ether, phenol were identified by IR, MS,'HNMR. It was showed that p-nitrophenylmethylenetripheny lphosphorane couldn't react with β-apo-8'-carotenal.

关 键 词：苯甲醚 苯酚 WITTIG反应 

分 类 号：O625.312[理学—有机化学]