前列腺移行区体积和移行区指数在诊断良性前列腺增生中的作用  

The significance of transition zone volume and transition zone index in the diagnosis of benign prostatic hyperplasia

作　　者：魏东[1] 苏洪学[1] 伍建业[1] 许进[1] 万奔[1] 那彦群[2] 

机构地区：[1]卫生部北京医院泌尿外科,北京100730 [2]北京大学医学部泌尿外科研究所

出　　处：《临床泌尿外科杂志》2002年第12期653-655,共3页Journal of Clinical Urology

摘　　要：目的 :评价前列腺移行区体积 (TZV)和移行区指数 (TZI)在诊断良性前列腺增生 (BPH)中的作用。方法 :采用经直肠超声测量 2 62例患者的前列腺体积 (TPV)和TZV ,其中A组 2 2 0例为有症状 ,未出现过尿潴留的BPH患者 ,B组 19例为反复出现尿潴留的BPH患者 ,对照组 2 3例为非BPH患者 ,并推算TZI(TZI =TZV/TPV)。以上患者同时接受了国际前列腺症状评分 (IPSS)、生活质量评分 (QOL)、最大尿流率 (Qmax)检查。所得数据进行统计学处理。结果 :A组、B组和对照组之间的TPV、TZV、TZI、IPSS、QOL、Qmax比较差异均有显著性意义 ,年龄与TPV和TZV有非常显著相关性 (分别r =0 .2 4,P <0 .0 1;r =0 .2 5 ,P <0 .0 1) ,与Qmax有非常显著负相关性 (r =- 0 .2 7,P <0 .0 1) ,与IPSS有显著相关性 (r =0 .15 ,P <0 .0 5 ) ,与QOL无相关性 (r =0 .11,P >0 .0 5 )。TPV与IPSS、QOL、Qmax有显著相关性 (r =0 .2 6,r =0 .2 0 ,r =- 0 .2 9,P均 <0 .0 5 ) ,而TZV和TZI与IPSS ,QOL ,Qmax均有非常显著相关性 (分别r =0 .40 ,r =0 .3 2 ,r =- 0 .43 ,P均 <0 .0 1;r =0 .5 1,r =0 .41,r =- 0 .5 2 ,均P <0 .0 1)。结论 :BPH患者随着年龄的增加 ,TPV、TZV、IPSS、QOL增加 ,Qmax减小。发生尿潴留的BPH患者 ,其TPV、TZV和TZI大于没有出现过?Purpose:To evaluate the significance of transition zone volume (TZV) and transition zone index (TZI, the ratio between TZV and total prostate volume ) in the diagnosis of benign prostatic hyperplasia ( BPH ).Methods:The study consisted of 262 men, whom were divided into three groups: group A for 220 BPH patients with symptom, but no urinary retention; group B for 19 BPH patients with urinary retention; and another 23 subjects with no BPH served as normal control. Results:All men completed the international prostate symptom score (IPSS), quality of life (QOL), peak urinary flow rate (Qmax), total prostate volume (TPV) and TZV by transrectal ultrasonography (TRUS), the TZI calculated. There were significant differences on TPV, TZV, TZI, IPSS, QOL and Qmax among group A, group B and control group. The age significantly correlated with TPV(r= 0.24 , P< 0.01 ) and TZV (r= 0.25 ,P< 0.01 ) respectively. The age correlated negtively with Qmax (r= -0.27 ,P< 0.01 ).There are weak correlation between age and IPSS (r= 0.15 ,P< 0.05 ) and no correlation between age and QOL (r= 0.11 , P> 0.05 ). There are a weak correlation between TPV and IPSS (r= 0.26 ), QOL(r= 0.20 ), Qmax (r= -0.29 ), respectively. But there are a strong correlation between TZV and IPSS (r= 0.04 ), QOL (r= 0.32 ), Qmax (r= -0.43 ) and also strong correlation between TZI and IPSS (r= 0.51 ), QLO (r= 0.41 ), Qmax (r= -0.52 ), respectively. Conclusions:①BPH patients' TPV, TZV, IPS, QOL increase and Qmax decreases with age.②TPV, TZV and TZI in BPH patients with urinary retention are larger than that in BPH patients with no urinary retention.③TZV and TZI were stronger correlative with IPSS, QOL, Qmax than TPV and should been stressed on diagnosis of BPH. ④TZI is a valued parameter in assessing BPH and maybe is useful to predict response to therapies.

关 键 词：移行区体积 移行区指数 诊断 良性前列腺增生 经直肠超声 

分 类 号：R697.32[医药卫生—泌尿科学]