高血压病人室壁中层缩短率降低的临床意义  

Clinical Implication of Subnormal Midwall Fraction Shortening of Left Ventricle in Patients with Essential Hypertension

作　　者：罗海明[1] 薛晓培[1] 张卫兴[1] 陆汉魁[1] 葛兆莺[1] 汪晓云[1] 王懋英[1] 梁瑞廉[1] 

机构地区：[1]上海市第六人民医院心内科,心超室,核医学科,上海200233

出　　处：《高血压杂志》2002年第6期520-522,共3页Chinese Journal of Hypertension

摘　　要：目的在原发性高血压病人中探讨室壁中层缩短分数 (mFS)的降低与早期心肌收缩功能减退与靶器官器质性损伤的相互关系。方法　比较mFS降低组与正常组病人静息位与最大药物负荷时左室射血分数 (EF)等的差异、以及心室质量、尿蛋白的组间差异。结果　静息位两组病人心功能无差异 ;mFS减低组的药物负荷核素心血池显象EF多有异常 ,伴心室质量增加及尿蛋白定性明显增加。结论　高血压病人mFS减退提示早期心室功能减退伴心脏。Objective To evaluate the relationship of subnormal midwall fractional shortening (mFS) with early damage of left ventricular(LV) systolic function and damage in target organs in patients with essential hypertension. Methods Radionuclide cineangiographic LV ejectoin fraction(EF) at rest and maximum dobatamine stress test, LV mass, urine protein were compared between groups with subnormal mFS and normal mFS. Results No difference of resting cardiac function between the two groups was found; subnormal mFS is associated with abnormal EF change of dobutamine stressed radionuclide ventriculography, increased LV mass, and increased urine protein. Conclusion Early damage of LV systolic function usually manifested as abnormal mFS, which often accompanied by impairment of LV and kidney.

关 键 词：高血压病 室壁中层缩短率 超声心动图 EH 心功能损害 

分 类 号：R544.1[医药卫生—心血管疾病]