左旋卡尼丁对冠心病PTCA术患者心肌的保护作用  

Therapeutic Effect of L-carnitine on the Treatment of Patients with PTCA

作　　者：陈国栋 曹茂荣[2] 任雨笙[3] 殷仁富[3] 

机构地区：[1]福建省晋江市中医院内科,晋江362200 [2]武警黑龙江总队医院内科,哈尔滨150076 [3]上海长征医院心内科,上海200003

出　　处：《同济大学学报（医学版）》2002年第5期413-415,共3页Journal of Tongji University(Medical Science)

摘　　要：目的　探讨左旋卡尼丁对冠心病PTCA术 (percutaneoustransluminalcoronaryangioplasty)心肌的保护作用。方法　比较 70例经左旋卡尼丁治疗的冠心病PTCA术患者血清CK MB、左室射血分数值的变化并与常规治疗的PTCA术患者进行比较。结果　应用左旋卡尼丁治疗的冠心病PTCA治疗患者的CK MB值较对照组明显减低 ,且CK MB峰值持续时间亦明显减低 (P <0 .0 5 ,P <0 .0 1) ,而左室射血分数值增高 (P =0 .0 0 0 3)。Objective To evaluate the effect of L?carnitine on the treatment of patients with PTCA.Methods Seventy patients with PTCA were treated with L?carnitine,the serum CK?MB was measured with L?carnitine and left ventricular ejection fraction was determined by echocardiography before and after PTCA in two groups.Results The serum CK?MB was decreased and EF was increased in the patients that treated with L?carnitine as compared to the patients with routine treatment.Conclusion The study suggested that L-carnitine might be an effective auxiliary medicine on the treatment of patients with PTCA.

关 键 词：左旋卡尼丁 冠心病 介入治疗 肌酸激酶同功酶 左室射血分数 经皮冠状动脉血管成形术 支架植入术 心肌保护 

分 类 号：R541.4[医药卫生—心血管疾病] R969.[医药卫生—内科学]