肾器官冷灌注过程中的热结构耦合模拟  

Thermal-Structure Coupling Simulation During Cold Perfusion of Kidney in Vitro

作　　者：诸凯[1,2] 王雅博[1,2] 安娜[1] 梁飞[1] 

机构地区：[1]天津商业大学天津市制冷技术重点实验室,天津300134 [2]天津大学中低温热能高效利用教育部重点实验室,天津300072

出　　处：《工程热物理学报》2014年第5期956-959,共4页Journal of Engineering Thermophysics

基　　金：国家自然科学基金自助项目(No.51076117)

摘　　要：生物组织在快速降温时,其内部温度梯度与热应力相关性的探索研究使人饶有兴趣。本文基于Ansys wvorkbench平台,对猪肾脏在冷灌注过程中,温度场与热应力场的耦合作用进行了探索性研究。重点探讨了肾脏快速降温时,因温度梯度所导致的生物热应力是否对细胞组织产生影响。研究结果表明:热变形沿血管形状呈现出梯度变化,靠近血管的热变形小于肾脏外缘;变形最大点在靠近肾脏表面两端的位置;温降速率是影响肾脏组织热应力和热形变的主要因素。研究方法以及结论对移植器官的冰温延时安全保存具有重要指导意义。During the rapid cooling of bio-tissue,the study of the internal temperature gradient and consequent thermal stress attracts people's attention.The temperature field and thermal stress field were coupling simulated through Ansys Workbench.The coupling effect of temperature field and thermal stress field was exploratory studied.This paper focuses on whether thermal stress resulting from temperature gradient impacts the bio-tissue.The result shows that thermal deformation presents gradient change along the shape of vessels.The deformation near the vessels is less than that of kidney surface.The maximum deformation takes place at the left or right tip of external surface.The cooling rate is the main factor effecting the thermal stress and deformation.The research methods and conclusion has an important guiding significance for subzero nonfreezing preservation of organs.

关 键 词：冷灌注 数值模拟 温度场 热应力场 热变形 

分 类 号：R692[医药卫生—泌尿科学] R318[医药卫生—外科学]