胺碘酮对心室慢性起搏阈值的影响  

Effect of Amiodarone on Chronic Ventricular Pacing Thresholds.

作　　者：姚均迪[1] 蒋逸风[1] 赵峰[1] 林晓耘[1] 吴宰盛[1] 

机构地区：[1]海军四一一医院,上海200081

出　　处：《中国心脏起搏与心电生理杂志》2002年第6期442-443,共2页Chinese Journal of Cardiac Pacing and Electrophysiology

摘　　要：为探讨胺碘酮对心室慢性起搏阈值的影响 ,对 12例安置心脏起搏器 3个月后伴发症状性心律失常患者 ,予胺碘酮治疗 ,用相应的程控仪测试用药前后的起搏阈值。药前 ,药后 1h、4h、1周和 2周的起搏阈值 (输出固定为2 .5V)分别为 0 .0 8± 0 .0 2 ,0 .0 8± 0 .0 1,0 .0 7± 0 .0 2 ,0 .0 8± 0 .0 1和 0 .0 8± 0 .0 2ms(P >0 .0 5 )。结论 :胺碘酮对心室慢性起搏阈值无影响。To evaluate the effect of amiodarone on chronic ventricular pacing threshold,12 patients with symptomatic arrhythmias,who had permanent cardiac pacemakers implanted for 3 months,were treated with amiodarone.Pacing thresholds were tested before and after amiodarone therapy using corresponding programmer.Results:The pacing threshold(output 2.5 V) before and 1 h,4 h,1 W,2 W after amiodarone given was 0.08±0.02,0.08±0.01,0.07±0.02,0.08±0.01 and 0.08±0.02 ms respectively( P >0.05).Conclusion:there is no effect of amiodarone on chronic ventricular pacing threshold.

关 键 词：胺碘酮 心室起搏阈值 永久心脏起搏 抗心律失常药 

分 类 号：R972.2[医药卫生—药品] R318.[医药卫生—药学]