下丘脑-垂体-性腺轴与衰老  

Hypothalamus-pituitary-gonad axis and senescence

作　　者：马渊[1] 张永祥[1] 

机构地区：[1]军事医学科学院毒物药物研究所,北京100850

出　　处：《军事医学科学院院刊》2002年第4期311-313,共3页Bulletin of the Academy of Military Medical Sciences

基　　金：国家重点基础研究发展规划项目 (G19990 5 44 0 1)资助

摘　　要：随着机体的衰老性腺的功能逐渐降低 ,而垂体促性腺激素水平升高 ,同时中枢神经系统对下丘脑_垂体_性腺 (HPG)轴的调节功能也发生了改变。性腺功能的减退并不能解释HPG轴在衰老过程中出现的许多变化 。In the process of aging the function of gonad decreases, while the secretion of gonadotropin is elevated, at the same time changes also take place in the modulation of hypothalamus_pituitary_gonad(HPG) axis controlled by the central nervous system. It is not satisfying to give answers to many changes of aging HPG axis by deterioration of gonad, many investigations indicate that the modification of the function of modulations has also taken part in the renovation of aging HPG axis.

关 键 词：下丘脑-垂体-性腺轴 阿片样肽类 神经调节剂 单胺神经递质 衰老 

分 类 号：R339.38[医药卫生—人体生理学]