古人类基因组与健康  

Hominid Genomes and Health

作　　者：刘瑞涛[1] 王檬[1] 贺红娟[1] 杨进[1] 

机构地区：[1]西北大学生命科学学院预防基因组医学研究所,西安710069

出　　处：《基因组学与应用生物学》2015年第6期1333-1338,共6页Genomics and Applied Biology

基　　金：国家自然科学基金(81272707)资助

摘　　要：随着第二代测序技术的发展,古人类基因组的研究进展迅速,各个古人类种群的起源与基因流向逐一揭晓,从中找出了对现代人基因有贡献的古人类种群,由此引发了对人类起源的重新思考与探究。更为重要的是古人类基因存在与疾病相关的序列信息,不仅为现代人医疗保健研究提供了参考,还有助于研究现代人疾病的发生。本文就近年来具有代表性的古人类基因组研究成果及其中与健康相关的重要发现作简要介绍。With the development of the second generation sequencing technology, enormous progresses had been acquired on hominid genomes research. The origins and flow of several hominind genomes had been revealed and a few of them contribute to modern human genomes, which triggerred the rethink and exploration of the origin of human beings. More importantly, the hominid genome sequence information was associated with the disease,which provided reference to modern healthcare resaerchs and contributed to uncover the occurrence of modern human diseases. Here, we had reviewd the results and significant discoveries correlated to health in present hominid genomes researchs.

关 键 词：古人类基因组 同源比对 健康 

分 类 号：Q987[生物学—遗传学]