体外循环心内直视术心肌肌钙蛋白Ⅰ的检测  

Determination of cTnⅠ under Cardiopulmonary Bypass

作　　者：聂荣华[1] 马军柏[1] 吴富常[1] 孙伯良[2] 

机构地区：[1]襄樊市中心医院心胸外科,襄樊441021 [2]襄樊市中心医院检验科,襄樊441021

出　　处：《华中科技大学学报（医学版）》2002年第6期708-709,共2页Acta Medicinae Universitatis Scientiae et Technologiae Huazhong

摘　　要：为评价不停跳与停跳体外循环心内直视术对心肌损伤的程度 ,分别对 2 0例不停跳和 2 8例停跳体外循环下房缺修补术患者术后围手术期血清心肌肌钙蛋白 (c Tn )浓度进行了对比研究。结果显示停跳组血清 c Tn 浓度明显高于不停跳组 (体外循环后 12、 2 4 h,P<0 .0 5 )。提示不停跳体外循环心内直视术具有心肌损伤小。To evaluate the perioperative release of cardiac troponin I (cTnⅠ) in beating and arrested heart under caridopulmonary bypass (CPB), 20 patients with beating heart and 28 patients with arrested heart, undergoing surgical closure of atrial septal defect (ASD) were studied. The results showed that the serum cTnⅠ concentration was significantly higher in arrested heart group than in beating heart group at 12 h, 24 h after CPB ( P <0.05). It was suggested that surgical closure of ASD with beating heart had a better effect for myocardial protection.

关 键 词：心脏外科手术 体外循环 肌钙蛋白I 心房间隔缺损 

分 类 号：R654.1[医药卫生—外科学] R654.[医药卫生—临床医学]