3,4-亚甲二氧基苯酚合成工艺研究  

Study on synthetic process of 3,4-methylene-dioxyphenol

作　　者：朱兆富[1] 沈喜海[1] 胡永利[1] 张志刚[1] 

机构地区：[1]河北职业技术师范学院化学系,河北昌黎066600

出　　处：《应用化工》2002年第5期39-41,共3页Applied Chemical Industry

摘　　要：报道了 3,4 亚甲二氧基苯酚的一种合成改进工艺。以邻苯二酚为原料 ,经亚甲基化、乙酰基化、过氧乙酸氧化、水解即获得 3,4 亚甲二氧基苯酚 ,总产率 5 2 7%。适宜的氧化条件 :n(过氧乙酸 )∶n(3,4 亚甲二氧基苯乙酮 ) =1 10∶1,2 0℃～ 30℃反应 4h ;适宜的水解条件 :5 %NaOH水溶液 10 0ml室温反应 4h。此工艺和传统工艺比较 。An improved process for the synthesis of 3,4 methylenedioxyphenol was reported. The pyrocatechol is used as raw material,through methylenation,acetylation,acetylperoxide oxidation,hydrolysis,the 3,4 methylenedioxyphenol was prepared,total yield is 52.7%.The optimum condition of oxidation were that the molar ratio of acetylperoxide and 3,4 methylenedioxy acetophenone was 1.10∶1,reaction temperature was 20 ℃～30 ℃,reaction time was 4 h.The hydrolysis is by 5% NaOH aqueous solution 100 ml at 20 ℃for 4 h.The experimental result revealed that the improved method was easy to obtain pure product and with good yield.

关 键 词：3 4-亚甲二氧基苯酚 合成工艺 研究 邻苯二酚 3 4-亚甲二氧基苯乙酮 过氧乙酸 

分 类 号：TQ243.12[化学工程—有机化工]