基于logistic回归分析探究影响神经源性膀胱患儿发生上尿路损害的相关因素  

Exploring the Related Factors Affecting Upper Urinary Tract Damage in Children with Neurogenic Bladder Based on logistic Regression Equation

作　　者：章奇 夏凡 黄碎毕 周维 ZHANG Qi;XIA Fan;HUANG Suibi;ZHOU Wei(Xiamen Children's Hospital,Xiamen 361006,China;不详)

机构地区：[1]厦门市儿童医院(复旦大学附属儿科医院厦门医院),福建厦门361006

出　　处：《中外医学研究》2025年第1期120-123,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:基于logistic回归分析探究影响神经源性膀胱患儿发生上尿路损害的相关因素。方法:回顾性选取2019年1月—2023年12月于厦门市儿童医院接受治疗的80例神经源性膀胱患儿,以患儿发生上尿路损害情况进行分组,将其分为受损组(n=56)与未受损组(n=24),收集患儿的相关资料,包括一般资料(年龄、性别、病程、病史等)、实验室检查(血常规、尿常规)、尿动力学检查及影像学检查等情况。采用多因素logistic回归分析影响患儿出现上尿路损害的相关独立因素。结果:单因素分析结果显示,两组年龄、性别、病程、脊柱手术史、中性粒细胞百分比、脊柱裂情况比较,差异无统计学意义(P>0.05);受损组尿白细胞数、膀胱厚度高于未受损组,淋巴细胞百分比低于未受损组,有发热、膀胱顺应性异常、膀胱过度活动比例高于未受损组,差异有统计学意义(P<0.05)。多因素logistic回归分析结果显示,尿白细胞数、膀胱顺应性、膀胱厚度均是影响神经源性膀胱患儿发生上尿路损害的独立危险因素(P<0.05)。结论:尿白细胞数、膀胱顺应性、膀胱厚度均是影响神经源性膀胱患儿发生上尿路损害的独立影响因素,临床上可根据患儿情况开展相关措施,进而降低患儿发生上尿路损害的风险。Objective:To explore the related factors affecting upper urinary tract damage in children with neurogenic bladder based on logistic regression equation.Method:A total of 80 children with neurogenic bladder treated in Xiamen Children's Hospital from January 2019 to December 2023 were retrospectively selected and grouped according to the incidence of upper urinary tract damage,and they were divided into damaged group(n=56)and undamaged group(n=24).Relevant data of these children were collected.Including general information(age,gender,course of disease,medical history,etc.),laboratory examination(blood routine,urine routine),urodynamic examination and imaging examination.Multivariate logistic regression equation was used to analyze the independent factors affecting the occurrence of upper urinary tract damage.Result:Univariate analysis showed that there were no significant differences in age,gender,course of disease,spinal surgery history,neutrophil percentage and spina bifida between the two groups(P>0.05).The urine white blood cell count and bladder thickness in the damaged group were higher than those in the undamaged group,the percentage of lymphocytes was lower than that in the undamaged group,and the proportion of fever,abnormal bladder compliance and overactive bladder were higher than those in the undamaged group,the differences were statistically significant(P<0.05).Multivariate logistic regression analysis showed that urinary white blood cell count,bladder compliance and bladder thickness were independent risk factors for upper urinary tract damage in children with neurogenic bladder(P<0.05).Conclusion:Urinary white blood cell count,bladder compliance and bladder thickness are all independent factors affecting upper urinary tract damage in children with neurogenic bladder.Relevant measures can be carried out clinically according to the conditions of children,so as to reduce the risk of upper urinary tract damage in children.

关 键 词：神经源性膀胱 儿童 上尿路损害 独立因素 

分 类 号：R726.9[医药卫生—儿科]