经导管介入与手术在小儿先天性心脏病室间隔缺损中的应用疗效及预后影响比较  

Comparison of the Effect and Prognosis of Transcatheter Intervention and Operation in Children with Ventricular Septal Defect in Congenital Heart Disease

作　　者：蔡海明 林志滨 张旭 林惠泉 CAI Haiming;LIN Zhibin;ZHANG Xu;LIN Huiquan(Zhangzhou Affiliated Hospital of Fujian Medical University,Zhangzhou 363000,China;不详)

机构地区：[1]福建医科大学附属漳州市医院,福建漳州363000

出　　处：《中外医学研究》2024年第36期75-78,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:在小儿先天性心脏疾病室间隔缺损中采取经导管介入、手术治疗,探索分析其临床应用疗效及预后影响。方法:选取2021年3月—2023年3年福建医科大学附属漳州市医院收治的68例患儿(均确诊为小儿先天性心脏病室间隔缺损)作为研究对象,根据患儿临床不同手术方式将其划分为对照组(外科手术)与观察组(经导管介入),每组各34例,比较不同手术治疗疗效及患儿预后。结果:观察组封堵成功率(治疗有效率)与对照组比较,差异无统计学意义(P>0.05);与对照组比较,观察组手术时间、术中出血量、总住院时间均更低,差异有统计学意义(P<0.05);与对照组比较,观察组术后并发症发生率更低,差异有统计学意义(P<0.05)。观察组手术后左室射血占数(LVEF)高于对照组,但是手术后左室收缩内径(LVEDD)、左室舒张末期内径(LVESD)均低于对照组,差异有统计学意义(P<0.05)。结论:经导管介入治疗小儿先天性心脏病室间隔缺损疗效显著,能提升患者术后心功能水平,降低并发症发生率。Objective:To explore and analyze the clinical efficacy and prognostic influence of transcatheter intervention and operation for ventricular septal defect in children with congenital heart disease.Method:A total of 68 children (all were diagnosed with ventricular septal defect in children with congenital heart disease) admitted to Zhangzhou Hospital,Fujian Medical University from March 2021 to March 2023 were selected as the study objects,and the children were divided into control group (surgical operation) and observation group (transcatheter intervention) according to different clinical surgical methods,with 34 cases in each group.The curative effect and prognosis of different surgical treatment were compared between the two groups.Result:There was no significant difference in the comparsion of success rate (effective rate) between the observation group and the control group (P>0.05).Compared with the control group,the operative time,intraoperative blood loss and total hospital stay in the observation group were lower,and the difference was statistically significant (P<0.05).Compared with the control group,the incidence of postoperative complications was lower in the observation group,and the difference was statistically significant (P<0.05).After operation,left ventricular ejection fraction (LVEF) in observation group was higher than that in control group,but left ventricular end-diastolic dimension (LVEDD) and left ventricular end-systolic diameter (LVESD) were lower than those in control group (P<0.05).Conclusion:Transcatheter intervention in the treatment of ventricular septal defect in children with congenital heart disease is effective,can improve the level of postoperative cardiac function,reduce the incidence of complications.

关 键 词：经导管介入 手术 小儿先天性心脏病 室间隔缺损 疗效及预后 

分 类 号：R54[医药卫生—心血管疾病]