细胞衰老在慢性心力衰竭中的作用机制研究进展  

A review of cellular senescence in chronic heart failure

作　　者：赵淑晴 赵莹 张宇 卢笑晖[2] ZHAO Shuqing;ZHAO Ying;ZHANG Yu;LU Xiaohui(Shandong University of Traditional Chinese Medicine,Jinan 250014,China;Geriatrics Center,Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250014,China)

机构地区：[1]山东中医药大学,山东省济南市250014 [2]山东中医药大学附属医院老年医学中心,山东省济南市250014

出　　处：《实用老年医学》2025年第1期93-97,共5页Practical Geriatrics

基　　金：卢氏内科流派传承工作室建设项目(lp2022-01);国家中医药管理局科技司共建科技项目(GZY-KGS-SD-2023-043)。

摘　　要：慢性心力衰竭(CHF)是心脏疾病的终末期发展阶段,临床上可由多种因素诱发,死亡率高,预后差。近年来人们发现,CHF的发生风险随着年龄的增加、细胞的衰老而增加,细胞衰老在CHF的发生发展中发挥重要的作用。因此,本文从不同类型的细胞衰老与CHF的关系综述细胞衰老在CHF中的作用与治疗进展,以期为CHF的研究和治疗提供新思路。Chronic heart failure(CHF)is the end stage of heart disease,which can be induced by various factors,with high mortality and poor prognosis.In recent years,it has been found that the risk of CHF increases with age and cell senescence,which plays an important role in CHF.Therefore,this article reviews the role and therapeutic progress of cellular senescence in CHF through the relationship between different types of cellular senescence and CHF,in order to provide new insights for the research and treatment of CHF.

关 键 词：细胞衰老 慢性心力衰竭 作用机制 

分 类 号：R541.6[医药卫生—心血管疾病]