纤维支气管镜肺泡灌洗术联合盐酸氨溴索对老年重症肺炎患者症状改善时间、血气分析指标的影响  

Influence of Fiberoptic Bronchoscopic Alveolar Lavage Combined with Ambroxol Hydrochloride on the Symptom Improvement Time and Blood Gas Analysis Indicators of Elderly Patients with Severe Pneumonia

作　　者：肖菲菲 寿志南[1] 香松林[1] XIAO Feifei;SHOU Zhinan;XIANG Songlin(Department of Respiratory and Critical Care Medicine,Guiyang First People's Hospital,Guiyang 550000,China)

机构地区：[1]贵阳市第一人民医院呼吸与危重症医学科,贵州贵阳550000

出　　处：《反射疗法与康复医学》2024年第19期89-92,共4页Reflexology And Rehabilitation Medicine

摘　　要：目的 探讨纤维支气管镜肺泡灌洗术联合盐酸氨溴索对老年重症肺炎患者症状改善时间、血气分析指标的影响。方法 选取2020年5月—2023年5月贵阳市第一人民医院收治的80例老年重症肺炎患者为研究对象,按随机数字表法将其分为对照组和观察组,每组40例。对照组患者给予盐酸氨溴索治疗,观察组患者在对照组基础上给予纤维支气管镜肺泡灌洗术治疗。比较两组的症状改善时间、血气分析指标、不良反应发生情况。结果 观察组体温恢复时间、咳嗽消失时间、肺湿啰音消退时间分别为(1.52±0.35)h、(3.42±1.22)h、(1.75±1.15)h,均短于对照组的(2.34±0.46)h、(5.34±1.79)h、(2.80±1.67)h,组间差异有统计学意义(P<0.05)。治疗后,观察组患者动脉血二氧化碳分压低于对照组,动脉血氧分压高于对照组,组间差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论纤维支气管镜肺泡灌洗术联合盐酸氨溴索可有效缩短老年重症肺炎患者症状改善时间,调节血气分析指标。Objective To explore the influence of fiberoptic bronchoscopic alveolar lavage combined with ambroxol hydrochloride on the symptom improvement time and blood gas analysis indicators of elderly patients with severe pneumonia.Methods Eighty elderly patients with severe pneumonia who were admitted to Guiyang First People's Hospital from May2020 to May 2023 were selected as the research objects,they were divided into a control group and an observation group according to the random number table method,with 40 cases in each group.Patients in the control group were treated with ambroxol hydrochloride,while patients in the observation group were given fiberoptic bronchoscopic alveolar lavage treatment on the basis of the treatment in the control group.The symptom improvement time,blood gas analysis indicators,and the occurrence of adverse reactions were compared between the two groups.Results The temperature recovery time,cough disappearance time and pulmonary rale regression time of the observation group were(1.52 ±0.35)h,(3.42±1.22)h and(1.75±1.15)h,which were shorter than(2.34±0.46)h,(5.34±1.79)h and(2.80±1.67)h of the control group,and the differences between the groups were statistically significant(P<0.05).After treatment,the partial pressure of arterial carbon dioxide in the patients of the observation group was lower than that in the control group,while the partial pressure of arterial oxygen was higher than that in the control group,and the differences between the groups were statistically significant(P<0.05).The incidence rates of adverse reactions in the two groups were compared,and the difference was not statistically significant(P>0.05).Conclusion The combination of fiberoptic bronchoscopic alveolar lavage and ambroxol hydrochloride can effectively shorten the symptom improvement time of elderly patients with severe pneumonia and regulate the blood gas analysis indicators.

关 键 词：老年重症肺炎 纤维支气管镜肺泡灌洗术 盐酸氨溴索 血气分析指标 动脉血二氧化碳分压 

分 类 号：R563.1[医药卫生—呼吸系统]