拉曼光谱技术在血液物种鉴别中的研究进展  

Research progress in Raman spectroscopy of bloodfor species identification

作　　者：王锦秀 胡春立 沈媛媛 张先彪 陈昌 田桢干 李深伟 WANG Jinxiu;HU Chunli;SHEN Yuanyuan;ZHANG Xianbiao;CHEN Chang;TIAN Zhengan;LI Shenwei(School of Public Health,Nanjing Medical University,Nanjing 211166,China;Shanghai International Travel Healthcare Center(Shanghai Customs Port Clinic),Shanghai 200335,China;Shanghai Photonic View Technology company,Ltd,Shanghai200443,China)

机构地区：[1]南京医科大学公共卫生学院,江苏南京211166 [2]上海国际旅行卫生保健中心(上海海关口岸门诊部),上海200335 [3]上海近观科技有限责任公司,上海201900

出　　处：《光散射学报》2024年第4期375-383,共9页The Journal of Light Scattering

基　　金：国家重点研发计划项目(编号:2022YFC2302801)。

摘　　要：拉曼光谱能够提供被分析样本的分子组成和结构信息,用于分析和检测生物组织的生化成分以及探索生物大分子的结构,具有无损、灵敏度高、检测快速等优势,广泛应用于法医鉴别、口岸样本检测等领域。本文简要概述了拉曼光谱的基本原理,并从检测方法、数据预处理和数据分类三个方面详细介绍了拉曼光谱技术在血液物种鉴别方面的发展及最新研究成果。同时,指出了该技术目前存在的一些局限性,讨论了在数据收集、处理、分类及图谱库建立方面遇到的挑战。最后,对拉曼光谱技术的未来研究与发展前景进行了展望,为该领域的后续研究提供必要参考。Raman spectroscopy can provide information on the molecular composition and structure of analyzed samples,used for analyzing and detecting the biochemical components of biological tissues and exploring the structure of biomolecules.It offers advantages such as non-destructiveness,high sensitivity,and rapid detection,and is widely applied in forensic identification and port sample testing.This review briefly outlines the basic principles of Raman spectroscopy and provides a detailed introduction to its advancements and latest research achievements in blood species identification from three aspects:detection methods,data preprocessing,and data classification.Additionally,it points out some current limitations of the technology and discusses the challenges encountered in data collection,processing,classification,and the establishment of spectral libraries.Finally,it explores the future research and development prospects of Raman spectroscopy,providing necessary references for subsequent research in this field.

关 键 词：拉曼光谱技术 血液 快速检测 化学计量学 物种鉴别 

分 类 号：O433[机械工程—光学工程] O657.37[理学—光学]