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作 者:刘文静[1] 姜瑾雯 王海韵 王顺兰 LIU Wenjing;JIANG Jinwen;WANG Haiyun;WANG Shunlan(The Second Clinical Medical School of Guangzhou University of Chinese Medicine,Guangzhou Guangdong 510405,China;Baiyum Hospital of the First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou Guangdong 510470,China;Guangdong Provincial Hospital of Chinese Medicine,Guangdong Guangzhou 510120,China;QIU Baoshan Provincial Famous Traditional Chinese Medicine Heritage Studio,Guangzhou Guangdong 510120)
机构地区:[1]广州中医药大学第二临床医学院,广东广州510405 [2]广州中医药大学第一附属医院白云医院,广东广州510470 [3]广东省中医院,广东广州510120 [4]邱宝珊省名中医传承工作室,广东广州510120
出 处:《新中医》2025年第1期104-109,共6页New Chinese Medicine
基 金:国家自然科学基金面上项目(82071024)。
摘 要:目的:通过循证医学方法系统评价电针治疗突发性耳聋的临床疗效。方法:系统检索中国知网、万方、维普、Pubmed、Embase、Web of Science、Cochrane Library数据库中自建库至2024年10月7日以来电针治疗突发性耳聋的随机对照试验,由2名研究者参考Cochrane协作网提供的偏倚风险评估工具,采用RevMan 5.3软件进行Meta分析。结果:共纳入8篇文献,样本量为638例,试验组321例,对照组317例。Meta分析结果显示,试验组电针治疗突发性耳聋的总有效率(RR=1.23,95%CI[1.07,1.41],P=0.003)、治愈率(RR=1.73,95%CI[1.28,2.34],P=0.0004)、眩晕总有效率(RR=1.25,95%CI[0.99,1.57],P=0.06)均高于对照组;试验组平均听阈值低于对照组(MD=-6.29,95%CI[-9.01,-3.56],P<0.00001),差异均有统计学意义(P<0.05)。结论:电针治疗突发性耳聋可以提高突发性耳聋总有效率、治愈率、眩晕总有效率,改善平均听阈值。Objective:To systematically evaluate the clinical effect of electroacupuncture in treating sudden deafness through evidence-based medicine methods.Methods:A systematic search was conducted on randomized controlled trials of electroacupuncture treatment for sudden deafness in databases such as CNKI,Wanfang,VIP,Pubmed,Embase,Web of Science,and Cochrane Library from the time of database establishment until October 7,2024.Two researchers referred to the bias risk assessment tool provided by the Cochrane Collaboration and conducted a Meta-analysis using RevMan 5.3 software.Results:A total of eight articles were included,with a sample size of 638 cases,including 321 cases in the trial group and 317 cases in the control group.The Meta-analysis results showed that the total effective rate(RR=1.23,95%CI[1.07,1.41],P=0.003),cure rate(RR=1.73,95%CI[1.28,2.34],P=0.0004),and total effective rate(RR=1.25,95%CI[0.99,1.57],P=0.06)of electroacupuncture treatment for sudden deafness in the trial group were higher than those in the control group;the average hearing threshold in the trial group was lower than that in the control group(MD=-6.29,95%CI[-9.01,-3.56],P<0.00001),and differences were significant(P<0.05).Conclusion:Electroacupuncture treatment for sudden deafness can improve the overall effective rate,cure rate,dizziness overall effective rate,and improve the average hearing threshold.
关 键 词:突发性耳聋 电针 随机对照试验 听阈值 Meta分析
分 类 号:R764.437[医药卫生—耳鼻咽喉科]
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