良性前列腺增生合并糖尿病患者经尿道前列腺电切术后内分泌指标及性功能水平的评价  

Evaluation of endocrine indexes and sexual function levels in patients with benign prostatic hyperplasia combined with diabetes after transurethral resection of prostate

作　　者：吴洪斌[1] 梁勇[2] 汪自力[3] Wu Hongbin;Liang Yong;Wang Zili(Department of Urology,Fushun County People’s Hospital,Zigong 643200,China)

机构地区：[1]富顺县人民医院泌尿外科,四川自贡643200 [2]自贡市第四人民医院泌尿外科 [3]成都大学附属医院泌尿外科

出　　处：《海军医学杂志》2024年第12期1282-1286,共5页Journal of Navy Medicine

基　　金：四川省科技计划项目(2021YFS0159)。

摘　　要：目的 评价良性前列腺增生合并糖尿病患者行经尿道前列腺电切术(TURP)后内分泌指标及性功能水平。方法 回顾性分析2020年1月至2023年1月纳入的100例良性前列腺增生患者的临床资料,根据糖尿病诊断标准将所有患者分为合并组(n=30)和未合并组(n=70)。2组患者均行TURP术。比较2组手术相关指标,同时测定其空腹血糖(FBG)、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL‐C)、高密度脂蛋白胆固醇(HDL‐C)、糖化血红蛋白(HbAlc),检测2组促卵泡生成素(FSH)、雌二醇(E_2)、泌乳素(PRL)、促黄体生成素(LH)、睾酮(T),评估简明男性性功能量表(BMSFI)评分,最后随访调查2组术后6个月并发症发生情况。结果 2组年龄、体重指数(BMI)、腰围、收缩压、舒张压、前列腺增生体积比较,差异均无统计学意义(P>0.05);2组术后导尿管留置时间、手术时间、腺体切除质量、术中出血量比较,差异均无统计学意义(P>0.05);合并组FBG、HbAlc、TC、TG、LDL‐C指标高于未合并组,HDL‐C指标低于未合并组(均P<0.05);2组FSH、LH、PRL指标比较差异无统计学意义(P>0.05);合并组E_2指标高于未合并组,T指标低于未合并组(均P<0.05);合并组BMSFI勃起功能、性欲、射精功能、问题评估、总体满意度评分低于未合并组(P<0.05);合并组并发症总发生率为30.01%,高于未合并组(11.44%),差异有统计学意义(P<0.05)。结论 良性前列腺增生合并糖尿病患者TURP后的内分泌指标异常,性功能障碍以及并发症发生风险增加,临床应对上述相关指标密切关注。Objective To evaluate the endocrine indexes and sexual function levels in patients with benign prostatic hyperplasia(BPH)combined with diabetes after transurethral resection of prostate(TURP).Methods The clinical data of 100 patients with BPH who underwent TURP from January 2020 to January 2023 were retrospectively analyzed.Among them,30 patients suffered from diabetes(diabetes group),and the other 70 patients did not have diabetes(control group).Surgery related indexes were compared between the two groups.Fasting blood glucose(FBG),total cholesterol(TC),triglycerides(TG),low‐density lipoprotein cholesterol(LDL‐C),high‐density lipoprotein cholesterol(HDL‐C),glycated hemoglobin(HbAlc),follicle stimulating hormone(FSH),estradiol(E2),prolactin(PRL),luteinizing hormone(LH),and testosterone(T)were measured.Sexual function was evaluated using the Brief Male Sexual Function Inventory(BMSFI).The incidence of complications was investigated during six‐month follow‐up. Results There was no statistically significant difference in the age, body mass index( BMI), waist circumference, systolicblood pressure, diastolic blood pressure, prostatic volume, retention time of urinary catheters, surgical time, glandular resectionquality, or intraoperative blood loss between the two groups (P>0. 05). The FBG, HbAlc, TC, TG, LDL‐C, and E2 in the diabetesgroup were higher than those in the control group, while the HDL‐C and T in the diabetes group were lower than those in the controlgroup( all P<0. 05). There was no statistically significant difference in the FSH, LH, or PRL between the two groups( P>0. 05). Thediabetes group had lower scores in erection, libido, ejaculation, problem assessment, and overall satisfaction than the control group(P<0. 05). The total incidence of complications in the diabetes group was higher than that in the control group (30. 01% vs.11. 44%, P<0. 05). Conclusion It is abnormal of endocrine indicators in patients with benign prostatic hyperplasia combined withdiabetes after TURP, and the risk

关 键 词：糖尿病 良性前列腺增生 经尿道前列腺电切术 内分泌指标 性功能障碍 

分 类 号：R697.3[医药卫生—泌尿科学]