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作 者:陈颖妍[1] CHEN Yingyan(Department of Otolaryngology,Dongguan Guancheng Hospital,Dongguan,Guangdong 523940,China)
机构地区:[1]东莞市莞城医院耳鼻咽喉科,广东东莞523940
出 处:《医药前沿》2025年第1期66-68,共3页Journal of Frontiers of Medicine
摘 要:目的比较窄带成像(NBI)技术与传统的白光成像(WLE)技术在支撑喉镜下行声带白斑切除时确定手术安全边界的效果。方法选取2021年10月—2023年9月于东莞市莞城医院接受治疗的32例中重度声带白斑患者,采用随机数字表法分为试验组和对照组各16例。试验组采用NBI辅助的支撑喉镜声带白斑切除术,对照组采用传统的WLE技术辅助的支撑喉镜声带白斑切除术。比较两组患者在不同技术下行手术并进行首次切除后所切除组织边缘的病理学分析结果。结果两组手术均安全无事故完成,对照组术中组织切缘的冷冻病理样本阳性切缘发生率为18.75%(3/16),试验组术中组织切缘的冷冻病理样本阳性切缘发生率为6.25%(1/16),试验组阳性切缘发生率低于对照组,但差异无统计学意义(P>0.05);试验组术中冷冻病理与术后病理诊断符合率为93.75%,术中冷冻病理诊断敏感度为50.00%、阳性预测值为100%;对照组术中冷冻病理与术后病理诊断符合率为75.00%,术中冷冻病理诊断敏感度为42.86%、阳性预测值为100%。试验组术中冷冻病理与术后病理诊断符合率、术中冷冻病理诊断敏感度高于对照组,但差异无统计学意义(P>0.05)。结论与传统WLE技术相比,采用NBI辅助支撑喉镜声带白斑切除手术能更准确地确定术中安全边界。Objective To compare the effectiveness of narrow band imaging(NBI)and traditional white light imaging(WLE)in determining the surgical safety boundary of vocal cord leukoplectomy under laryngoscope.Methods A total of 32 patients with moderate to severe vocal cord leukodes who were treated in Dongguan Guancheng Hospital from October 2021 to September 2023 were selected and divided into the experimental group and the control group with 16 cases in each group by random number table method.The experimental group was treated with NBI assisted support laryngoscope and the control group was treated with WLE assisted support laryngoscope.The results of pathological analysis of the tissue margins of the two groups were compared after the first resection with different techniques.Results The operation was completed safely and without accident in both groups.The incidence of positive margins in frozen pathological samples of tissue during operation was 18.75%(3/16)in the control group and 6.25%(1/16)in the experimental group.The incidence of positive margins in the experimental group was lower than that in the control group,but the difference was not statistically significant(P>0.05).In the experimental group,the coincidence rate of intraoperative frozen pathology and postoperative pathological diagnosis was 93.75%,the sensitivity of intraoperative frozen pathological diagnosis was 50.00%,and the positive predictive value was 100%.In the control group,the coincidence rate of intraoperative frozen pathology and postoperative pathological diagnosis was 75.00%,the sensitivity of intraoperative frozen pathological diagnosis was 42.86%,and the positive predictive value was 100%.The coincidence rate of intraoperative frozen pathology and postoperative pathological diagnosis and the sensitivity of intraoperative frozen pathology in the experimental group were higher than those in the control group,but the difference was not statistically significant(P>0.05).Conclusions Compared with traditional WLE technique,NBI assisted laryngosco
分 类 号:R767[医药卫生—耳鼻咽喉科]
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