高龄不孕女性生育压力及其影响因素分析  

Analysis of fertility pressure and its influencing factors in elderly infertile women

作　　者：朱俞欢 廖兰英 周玲[1] 宋秋兰 何杨秋 黄福辉 ZHU Yuhuan;LIAO Lanying;ZHOU Ling;SONG Qiulan;HE Yangqiu;HUANG Fuhui(Reproductive Medical Center,the Second Nanning People’s Hospital,Guangxi Zhuang Autonomous Region,Nanning 530031,China)

机构地区：[1]南宁市第二人民医院生殖医疗中心,广西南宁530031

出　　处：《妇儿健康导刊》2024年第24期184-188,共5页JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE

基　　金：广西壮族自治区卫生健康委员会自筹经费科研课题(Z20200868;Z-A20231184)。

摘　　要：目的探讨高龄不孕女性的生育压力及其影响因素。方法选取于2020年7月至2021年7月在南宁市第二人民医院生殖医疗中心行体外受精-胚胎移植(IVF-ET)的368例不孕女性作为研究对象,最终纳入有效数据360例,根据女性年龄不同分为A组(25~<35岁)、B组(35~<40岁)与C组(40~<45岁),每组各120例,比较不同年龄女性的生育压力,并分析导致高龄不孕女性生育压力的影响因素。结果B组与C组各方面生育压力评分均高于A组,差异有统计学意义(P<0.05);C组各方面生育压力评分均高于B组,差异有统计学意义(P<0.05)。单因素分析显示,不同居住地、结婚时间、不孕年限、生育史、流产史高龄不孕女性的生育压力比较,差异有统计学意义(P<0.05)。多因素分析显示,居住地(农村)、结婚时间(≥5年)、不孕年限(≥5年)、无生育史、流产次数(≥2次)均是高龄不孕女性生育压力的影响因素(OR=2.392、2.883、6.821、4.285、4.808,P<0.05)。结论高龄不孕女性的生育压力与居住地、结婚时间、不孕年限、生育史、流产次数相关,IVF-ET治疗中应注重评估影响高龄不孕女性的生育压力和心理状态,尽早采取措施干预,缓解其生育压力,提高IVF-ET治疗成功率。Objective To explore the fertility pressure and its influencing factors in elderly infertile women.Methods A total of 368 infertile women who underwent in vitro fertilization and embryo transfer(IVF-ET)in the Reproductive Medical Center of the Second Nanning People’s Hospital from July 2020 to July 2021 were selected as the study subjects.Finally,360 cases of valid data were included.They were divided into group A(25-<35 years old),group B(35-<40 years old)and group C(40-<45 years old)according to different female ages.There were 120 women in each group,and the fertility pressure of women of different ages was compared.The influencing factors leading to high fertility pressure of elderly infertile women were analyzed.Results The scores of fertility pressure in group B and group C were higher than those in group A,and the differences were statistically significant(P<0.05).The scores of all aspects of fertility pressure in group C were higher than those in group B,and the differences were statistically significant(P<0.05).Univariate analysis showed that there was significant difference in fertility pressure among different places of residence,marriage time,infertility years,fertility history,and number of abortions(P<0.05).Multifactorial analysis showed that place of residence(rural area),marriage time(≥5 years),infertility years(≥5 years),no childbearing history,and number of abortions(≥2 times)were all influencing factors of fertility pressure in elderly infertile women(OR=2.392,2.883,6.821,4.285,4.808,P<0.05).Conclusion The fertility pressure of elderly infertile women is related to residence,marriage time,infertility years,reproductive history,and number of abortions.In the treatment of IVF-ET,attention should be paid to evaluating the fertility pressure and psychological state of elderly infertile wom en,and early intervention m easures should be taken to relieve their fertility pressure and improve the succ ess rate of IVF-ET treatment.

关 键 词：高龄 不孕症 生育压力 影响因素 生育史 

分 类 号：R711.6[医药卫生—妇产科学]