Conditionally restricted fluorescent probe for Fe^(3+)and Cu^(2+)based on the naphthalimide structure  

基于萘酰亚胺结构的条件限制型Fe^(3+)和Cu^(2+)荧光探针

作　　者：ZHU Yuan ZHANG Xiaoda WANG Shasha WEI Peng YI Tao 祝愿;张晓达;王莎莎;魏鹏;易涛(东华大学化学与化工学院,上海201620)

机构地区：[1]College of Chemistry and Chemical Engineering,Donghua University,Shanghai 201620,China

出　　处：《无机化学学报》2025年第1期183-192,共10页Chinese Journal of Inorganic Chemistry

基　　金：国家自然科学基金(No.22371038,22177019)资助。

摘　　要：To address the lack of systematic studies on heavy metal fluorescent probes in typical buffer solutions,this study developed a Fe^(3+)and Cu^(2+)fluorescent probe,DHU‑NP‑4,based on a naphthalimide fluorophore.Comparative analysis of the probe's performance in various buffer systems revealed that buffers with high organic content are unsuitable for evaluating such probes.Furthermore,the pH of the solvent system was found to significantly influence the probe's behavior.Under highly acidic conditions(pH≤2),DHU‑NP‑4 exhibited exceptional specificity for Fe^(3+),while in alkaline conditions,it demonstrated high specificity for Cu^(2+).Leveraging these properties,the probe enabled the quantitative detection of Fe^(3+)and Cu^(2+)in solution.为了解决当前重金属荧光探针缺乏在典型缓冲溶液中系统研究的问题,本研究开发了一种基于萘酰亚胺荧光团的Fe^(3+)和Cu^(2+)荧光探针DHU‑NP‑4。通过对比不同缓冲溶液对探针性能的影响,发现含大量有机成分的缓冲液不适用于评估此类探针,同时溶剂体系的pH值对探针性能具有显著影响。在较高酸性条件下(pH≤2),DHU‑NP‑4对Fe^(3+)展现出优异的特异性响应;而在碱性条件下,则对Cu^(2+)显示出高度的特异性。基于这些发现,本研究利用DHU‑NP‑4实现了溶液中Fe^(3+)和Cu^(2+)的定量检测。

关 键 词：fluorescent probe NAPHTHALIMIDE copper(Ⅱ)ion iron(Ⅲ)ion buffer solution 

分 类 号：O614.811[理学—无机化学] O614.121[理学—化学]