夜间间歇性缺氧相关评估指标的研究进展  

Progress in the assessment of indicators related to nocturnal intermittent hypoxia

作　　者：谢葵 郭华 崔小川 XIE Kui;GUO Hua;CUI Xiaochuan(Department of General Practice and Sleep Center,the Affiliated Wuxi People’s Hospital of Nanjing Medical University(Wuxi Medical Center of Nanjing Medical University),Wuxi 214000,China)

机构地区：[1]南京医科大学附属无锡人民医院(南京医科大学无锡医学中心)全科医学科睡眠中心,江苏无锡214000

出　　处：《南京医科大学学报(自然科学版)》2025年第1期91-97,126,共8页Journal of Nanjing Medical University(Natural Sciences)

基　　金：国家自然科学基金(82200106);无锡市卫健委新“三名”战略重点扶持项目(SMZLBRZKQK)。

摘　　要：阻塞性睡眠呼吸暂停是一种常见的疾病,其患病率正在逐年上升,由其引发的夜间间歇性缺氧与多种不良健康结局有密切关系,因此,探索简单、可靠而全面的夜间间歇性缺氧评估指标,一直是近年来研究的热点。文章总结了目前夜间间歇性缺氧相关指标的不同评估方法,包括表征间歇性缺氧的频率(氧饱和度下降指数)、持续时间(氧饱和度低于90%时间、饱和度损伤时间)、低氧幅度(最低血氧饱和度、血氧饱和度下降幅度)等单项评估指标及低氧负荷、低氧负荷指数、低氧负担、睡眠呼吸障碍指数等综合性评估指标。Obstructive sleep apnea is a common disease,the prevalence of which is increasing year by year,and the nocturnal intermittent hypoxia triggered by it is closely related to a variety of adverse health outcomes,therefore,it is a hotspot to search for a simple,reliable and comprehensive index to assess intermittent night hypoxia in recent years.In this paper,we summarized the different evaluation methods of the indexes related to nocturnal intermittent anoxia,including the frequency(oxygen saturation decline index),duration(time when oxygen saturation is below 90%and saturation damage time),and hypoxia amplitude(lowest oxygen saturation,oxygen saturation decline amplitude),etc,and comprehensive assessment indicators such as hypoxic load,hypoxic load index,hypoxic load,and sleep-disordered breathing index,etc.

关 键 词：夜间间歇性缺氧 阻塞性睡眠呼吸暂停 评估指标 

分 类 号：R766[医药卫生—耳鼻咽喉科]